Daily non-political popular news in brief.

BERT and ERNI proteins control brain development

The vertebrate nervous system develops from the neural plate, defined by the transcription factor Sox2. This paper uncovers a mechanism that regulates the timing of Sox2 expression, involving interactions between several proteins and chromatin remodeling.

Read more »

Keywords: bert, erni, proteins, control, brain, development, protein

« Previous | Next »

Similar news on "BERT and ERNI proteins control brain development":

1. BERT tells ERNI it's time to grow a brain
   01-08-2008 · EurekAlert!
   UCL scientists have discovered how two proteins called BERT and ERNI interact in embryos to control when different organ systems in the body start to form, deepening our understanding of the development of the brain and nervous system and stem cell behaviour.
   Similar news · Read more »
   
2. Weizmann Institute scientists develop a general 'control switch' for protein activity
   06-19-2007 · EurekAlert!
   Since malfunctioning proteins can cause disease, the study of protein structure and function can lead to the development of drugs and treatments for numerous disorders. Now, Weizmann scientists have developed a unique "switch" that can control the activity of any protein, raising it several-fold or stopping it almost completely. The method provides researchers with a simple and effective tool for exploring the function of unknown proteins.
   Similar news · Read more »
   
3. Researchers map signaling networks that control neuron function
   01-28-2008 · EurekAlert!
   In the first large-scale proteomics study of its kind, researchers at the University of California-San Diego School of Medicine have mapped thousands of neuronal proteins to discover how they connect into complex signaling networks that guide neuron function. Their research -- using quantitative mass spectrometry, computational software and bioinformatics to match the proteins to their cellular functions -- may lead to a better understanding of brain development, neurodegenerative diseases, and spinal cord regeneration.
   Similar news · Read more »
   
4. Rutgers scientists discover brain cell development process implicated in mental retardation
   07-31-2007 · EurekAlert!
   Scientists at Rutgers University have discovered a biological process in brain cell development that may help explain some causes of mental retardation. This understanding may one day help other researchers develop therapies that can reduce specific forms of retardation. Proteins of the Rho family, when excessively present in developing brain cells known as neurons, inhibit another protein, called cypin, that promotes healthy neuron development.
   Similar news · Read more »
   
5. Missing protein may be key to autism
   12-05-2007 · Massachusetts Institute of Technology (MIT)
   A missing brain protein that helps in the development of synapses may be one of the culprits behind autism and other brain disorders, according to researchers at MIT's Picower Institute for Learning and Memory.
   Similar news · Read more »
   
6. Scripps research scientists identify new regulatory mechanism for critical protein signaling domain
   04-05-2007 · EurekAlert!
   In a study with far-reaching implications, scientists at the Scripps Research Institute and other institutions have for the first time identified a new in vivo regulatory mechanism for the PH Domain, a component of many proteins that allows them to move from a cell's interior to the cell membrane in response to stimulation of cell surface receptors. The findings offer a promising avenue for the development of novel therapies for immunodeficiency or autoimmune diseases.
   Similar news · Read more »
   
7. UWM brain research supports drug development from jellyfish protein
   10-27-2006 · EurekAlert!
   With the research support from the University of Wisconsin-Milwaukee, a Wisconsin biotech company has found that a compound from a protein found in jellyfish is neuroprotective and may be effective in treating neurodegenerative diseases.
   Similar news · Read more »
   
8. Study shows how embryos regulate vitamin A derivatives
   11-19-2007 · EurekAlert!
   Human embryos that get too much or too little retinoic acid, a derivative of Vitamin A, can develop into babies with birth defects. New research at UC-Irvine shows for the first time how embryonic cells may regulate levels of retinoic acid, giving scientists insight into how it acts as a signal between cells to control development of the brain, limbs and many other tissues in embryos.
   Similar news · Read more »
   
9. Copper damages protein that defends against Alzheimer's
   11-06-2007 · EurekAlert!
   Copper can damage a molecule that escorts out of the brain a substance called amyloid beta that builds up in toxic quantities in the brains of people with Alzheimer's disease. The new findings demonstrate one way in which copper might contribute to the development of the disease, though scientists say much more research needs to be done to clarify what role, if any, copper ultimately plays.
   Similar news · Read more »
   
10. Penn researchers discover how microRNAs control protein synthesis
    07-09-2007 · EurekAlert!
    While most RNAs work to create, package and transfer proteins as determined by the cell's immediate needs, miniature pieces of RNA, called microRNAs (miRNAs) regulate gene expression. Recently, researchers from the University of Pennsylvania School of Medicine determined how miRNAs team up with a regulatory protein to halt protein production.
    Similar news · Read more »