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Breast cancer risk varies significantly among BRCA1 and BRCA2 carriers

There is a broad variation in the risk of developing breast cancer among people who carry the BRCA1 and BRCA2 gene mutation, according to a study in the Jan. 9/16 issue of JAMA.

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Keywords: breast, cancer, risk, varies, significantly, brca1, brca2, carriers, vary, carrier

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1. Breast cancer risk varies among women who are carriers of BRCA1 and BRCA2 gene mutations
   01-08-2008 · EurekAlert!
   Breast cancer risk varies widely among women who are carriers of the BRCA1 and BRCA2 mutations, according to a new study published in the Jan. 9, 2008, issue of the Journal of the American Medical Association.
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2. Ashkenazi ovarian cancer patients with BRCA mutations live longer than those with normal gene
   01-01-2008 · EurekAlert!
   Israeli investigators have found that Ashkenazi Jewish women with ovarian cancer who have mutations in the BRCA1 or BRCA2 genes lived significantly longer than Ashkenazi Jewish ovarian cancer patients without these mutations. After up to nine years of follow-up, BRCA1/2 mutation carriers were 28 percent less likely to die from the disease, even though women with the BRCA mutations are significantly more likely to develop ovarian and breast cancers.
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3. Benefit of cancer prevention surgery differs between women with BRCA1 and BRCA2 mutations
   02-11-2008 · EurekAlert!
   The surgical removal of the ovaries has been widely adopted as a cancer-risk-reducing strategy for women with either BRCA1 or BRCA2 mutations. A new multicenter study led by researchers at Memorial Sloan-Kettering Cancer Center is the first prospective examination of the impact of this procedure in which BRCA2 mutation carriers were analyzed separately from BRCA1 mutation carriers.
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4. Personalized medicine can cut breast cancer risk
   02-15-2008 · EurekAlert!
   The time has come for breast cancer risk assessment, counseling and genetic testing to move from cancer specialists to the realm of primary care. A growing body of evidence has documented the benefits of preventive measures for high-risk women including those with mutations in the BRCA1 and BRCA2 genes. Referral for cancer-risk assessment and BRCA testing in the primary care setting is a necessary step towards personalized medicine for women at risk.
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5. BRCA2 carriers at increased risk for deadly form of prostate cancer
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   12-05-2006 · EurekAlert!
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