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Stem cells make bone marrow cancer resistant to treatment
01-11-2008 · EurekAlert!Scientists at the Johns Hopkins Kimmel Cancer Center say they have evidence that cancer stem cells for multiple myeloma share many properties with normal stem cells and have multiple ways of resisting chemotherapy and other treatments.
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Keywords: stem, cells, make, bone, marrow, cancer, resistant, treatment, cell
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- A faster way to recover from chemotherapy and marrow transplant
06-20-2007 · EurekAlert!
Researchers at Children's Hospital Boston report finding a practical way to increase stem cells in blood, suggesting a possible treatment to help patients recover from chemotherapy or bone marrow transplant for cancer, regaining immune function more quickly. The discovery, reported in the June 21 Nature and made possible through high-volume drug screening in fish, marks the first time stem-cell production has been induced by a small-molecule drug.
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- Stress may help cancer cells resist treatment, research shows
04-10-2007 · EurekAlert!
Scientists from Wake Forest University School of Medicine are the first to report that the stress hormone epinephrine causes changes in prostate and breast cancer cells that may make them resistant to cell death.
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- Adult stem cell application effective in treatment of peripheric vascular disease
01-24-2008 · EurekAlert!
Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.
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- First human trial tests stem-cell-based treatment for heart attacks
03-25-2007 · EurekAlert!
Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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- Cancer cells enlist adult stem cells to promote metastasis
10-31-2007 · Massachusetts Institute of Technology (MIT)
MIT and Whitehead institute scientists have managed to facilitate metastasis, finding evidence that some breast cancer cells recruit normal adult stem cells from bone marrow and force them to secrete a protein that fosters cancer cell movement and invasion.
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- Drug combination slows progression of treatment resistant bone marrow cancer
12-12-2006 · EurekAlert!
Combining a newly formulated drug with one that is already a standard treatment slows the progression of multiple myeloma, an advanced cancer of the bone marrow cells, according to a clinical trial led by a University of North Carolina at Chapel Hill School of Medicine researcher.
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- Type of stem cell found to reside in transplanted lungs
03-08-2007 · EurekAlert!
A new study involving a type of stem cells from the lungs of transplant patients demonstrates for the first time that these progenitor cells reside in adult organs and are not derived from bone marrow, which leads to the possibility that the cells may be able to help with the rejection of donated organs and with various kinds of lung disease.
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- Adult stem cell heart attack study updated at American Society for Hematology Meeting
12-11-2007 · EurekAlert!
Doctors are using patients' own bone marrow stem cells (progenitor cells) to treat the damage to cardiac muscle after a heart attack in a study at Emory University School of Medicine. The study investigators will update their colleagues on its progress at the American Society of Hematology meeting in Atlanta next week.
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- Jefferson scientists find aging gene also protects against prostate cancer development
11-27-2006 · EurekAlert!
Cancer researchers have found that a gene that is involved in regulating aging also blocks prostate cancer cell growth. They have shown that the enzyme SIRT1 can block the growth of treatment-resistant prostate cancer cells that overexpress a mutation for the androgen receptor. The scientists hope the newly found connection will aid in better understanding the development of prostate cancer and lead to new drugs against the disease.
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- Cancer-killing invention also harvests stem cells
01-04-2007 · EurekAlert!
Prof Michael King of the University of Rochester has invented a device that filters the blood for cancer and stem cells. When he captures cancer cells, he kills them. When he captures stem cells, he harvests them for later use in tissue engineering, bone marrow transplants, and other health applications. This is a non-controversial way of obtaining stem cells that can be differentiated into other, useful cells.
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