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Study helps explain how allergic reactions are triggered
01-14-2008 · EurekAlert!In demonstrating that a group of calcium ion channels play a crucial role in triggering inflammatory responses, researchers at Beth Israel Deaconess Medical Center have not only solved a longstanding molecular mystery regarding the onset of asthma and allergy symptoms, but have also provided a fundamental discovery regarding the functioning of mast cells.
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- Protein suppresses allergic response in mice
11-18-2007 · EurekAlert!
A protein in mice known as RGS13 suppresses allergic reactions, including the severe, life-threatening allergic reaction known as anaphylaxis, according to scientists at NIAID. Because RGS13 is also a protein found in humans and is expressed in only a limited number of cells -- including the immune system's mast cells that are central to allergic reactions -- scientists believe the protein may be a target for developing drugs to treat and prevent certain allergic reactions, including anaphylaxis.
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- UVA researchers explain cell response to skin-damaging UV rays
10-01-2007 · EurekAlert!
Researchers at the University of Virginia Health System have published a new study that helps scientists around the world expand the body of knowledge on how cells protect themselves (or not) from DNA damage caused by UV rays. Their study reveals part of a 'simple switch' mechanism inside cells, triggered by UV exposure from the sun, that helps our cells survive and thrive after being exposed. This mechanism involves an unanticipated connection between several proteins in the cell, the researchers discovered.
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- Key molecular signaling switch involved in allergic disease identified
10-29-2006 · EurekAlert!
A research team has identified a key enzyme responsible for triggering a chain of events that results in allergic reaction, according to new study findings published online this week in Nature Immunology.
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- Pilot study successful in taming allergic reactions to food
11-22-2006 · EurekAlert!
Children who were allergic to eggs were able to essentially overcome their allergy by gradually consuming increased quantities of eggs over time, researchers at Duke University Medical Center and the University of Arkansas for Medical Sciences have found in a small pilot study.
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- Newer contrast agents safe for children
06-07-2007 · EurekAlert!
Allergic-like reactions to newer iodine-containing contrast agents (nonionic contrast media), are rare in children according to a recent study conducted by researchers from the University of Michigan Medical Center and C.S. Mott Children's Hospital, both in Ann Arbor.
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- Cannabinoids produced in the human body have an anti-inflammatory effect
06-07-2007 · EurekAlert!
Endocannabinoids seem to play an important role in regulating inflammation processes. Scientists from the University of Bonn have discovered this in experiments on mice. Their results will be published in the distinguished scientific journal Science on Friday, June 8. The study may also have implications for therapy. In animal experiments, a solution with an important component made from cannabis reduced allergic reactions of the skin.
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- Lasers Shine Light on Chemical Reactions
11-22-2006 · Brookhaven National Laboratory
Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have been using a high-resolution laser technique to learn how molecules absorb light and fall apart during photodissociation reactions - chemical decomposition reactions triggered by light. Studying the atomic-level details of such reactions allows scientists to test and refine theories of chemical reactions, and may help them in their quest to use light to control reaction outcomes.
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- Allergic reactions to gadolinium-based contrast agents are rare, study finds
12-28-2007 · EurekAlert!
Allergic-like reactions to gadolinium-containing contrast injections in adults and pediatric patients (those younger than 19 years of age) are rare, according to a recent study conducted by researchers at the University of Michigan Health Systems in Ann Arbor. "When these reactions do occur, most of them are mild," said Jonathan R. Dillman, M.D., lead author of the study.
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- Protein a possible key to allergy and asthma control
01-02-2008 · EurekAlert!
Activating a protein found on some immune cells seems to halt the cells' typical job of spewing out substances that launch allergic reactions, a study by Johns Hopkins researchers suggests. The findings could eventually lead to new treatments for allergic reactions ranging from annoying bouts of hay fever to deadly asthma attacks.
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- Type 1 diabetes triggered by 'lazy' regulatory T-cells: McGill researchers
01-15-2008 · EurekAlert!
A research team led by Dr. Ciriaco A. Piccirillo of McGill University's Department of Microbiology and Immunology has discovered that in some individuals, the specialized immunoregulatory T-cells that regulate the body's autoimmune reactions may lose their effectiveness and become "lazy" over time, leading to the onset of type 1 diabetes. The study was published in the January 2008 edition of the journal Diabetes.
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