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Smoking related to long-term risk and progression of age-related eye disease

Smokers appear to have an increased long-term risk and greater progression of the eye disease age-related macular degeneration, according to a report in the January issue of Archives of Ophthalmology, one of the JAMA/Archives journals.

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Keywords: smoking, related, long-term, risk, progression, age-related, eye, disease, long, term, age

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1. Smoking may strongly increase long-term risk of eye disease
   08-13-2007 · EurekAlert!
   Current and past smokers appear to have a higher risk of developing late age-related macular degeneration than those who have never smoked, according to a report in the July issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
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2. New nationwide study will evaluate effect of antioxidants and fish oil on progression of AMD
   10-12-2006 · EurekAlert!
   This new study, called the Age-Related Eye Disease Study 2 (AREDS2), will build upon results from the earlier Age-Related Eye Disease Study (AREDS). The original study results were released five years ago today. The study found that high-dose antioxidant vitamins and minerals (vitamins C and E, beta-carotene, zinc and copper), taken by mouth, reduced the risk of progression to advanced AMD by 25 percent, and the risk of moderate vision loss by 19 percent.
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3. Common genetic variants linked with progression to advanced forms of AMD
   04-24-2007 · EurekAlert!
   Variations of two common genes are associated with progression to more advanced forms of age-related macular degeneration, and factors such as smoking and being overweight greatly increase this risk, according to a study in the April 25 issue of JAMA.
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4. Gene variant increases risk of blindness
   07-18-2007 · EurekAlert!
   Researchers have found a gene variant that can more than double the risk of developing the degenerative eye disease, age-related macular degeneration.
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5. Elevated inflammatory marker may be linked to increased risk of age-related eye disease
   10-08-2007 · EurekAlert!
   High blood levels of C-reactive protein, a substance linked to inflammation, appear to be associated with an increased risk for age-related macular degeneration, according to a report in the October issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
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6. Nutrients lutein and zeaxanthin associated with reduced risk for age-related eye disease
   09-10-2007 · EurekAlert!
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7. New treatment for age-related macular degeneration within sight
   11-29-2007 · EurekAlert!
   With 8 million people at high risk for advanced age-related macular degeneration, researchers from Harvard and Japan discovered that the experimental drug, endostatin, may be the cure. A research report published in the December 2007 issue of The FASEB Journal, describes how giving endostatin to mice significantly reduced or eliminated abnormal blood vessel growth within the eye, which is ultimately why the disease causes blindness.
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8. New gene linked to macular degeneration risk
   10-19-2006 · EurekAlert!
   Researchers at the John A. Moran Eye Center at the University of Utah have identified a gene called HTRA1 that contributes to a major risk of age related macular degeneration, the most common cause of irreversible vision loss in the developed world. The discovery of this gene allows anyone to take a simple blood test to find out if they are up to 700 percent more likely to develop AMD than the average person.
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9. American Journal of Lifestyle Medicine from SAGE explores how lifestyle affects heart disease
   01-11-2007 · EurekAlert!
   Cardiovascular disease is the most common cause of death in the United States. Although some risk factors, such as age and heredity, cannot be controlled, many factors, including smoking, cholesterol, blood pressure, obesity and inactivity can be modified, thus, lowering the risk. This lifestyle concern is thoroughly explored in the headline article of the debut issue of the new American Journal of Lifestyle Medicine (AJLM) published by SAGE.
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10. Scientists discover zinc link to a leading cause of blindness
    03-22-2007 · EurekAlert!
    Scientists at the University of Texas Medical Branch at Galveston and Neurobiotex, Inc. have found high levels of zinc in amyloid plaque deposits in the eye that are an indication of age-related macular degeneration (AMD). The discovery marks an additional similarity between AMD plaques and those seen in Alzheimer's disease and could facilitate the development of effective treatments for AMD.
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