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Penn engineers create carbon nanopipettes that are smaller than cells and measure electric current
01-15-2008 · EurekAlert!University of Pennsylvania engineers and physicians have developed a carbon nanopipette thousands of times thinner than a human hair that measures electric current and delivers fluids into cells. Researchers developed this tiny carbon-based tool to probe cells with minimal intrusion and inject fluids without damaging or inhibiting cell growth.
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Keywords: penn, engineers, create, carbon, nanopipettes, smaller, cells, measure, electric, current, engineer, nanopipette, cell
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- Elephants' fear of angry bees could help to protect them
10-08-2007 · EurekAlert!
At a time when encroaching human development in former wildlife areas has compressed African elephants into ever-smaller home ranges and increased levels of human-elephant conflict, a study in the Oct. 9 issue of Current Biology, a publication of Cell Press, suggests that strategically placed beehives might offer a low-tech elephant deterrent and conservation measure.
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- Brown scientists take the petri dish to new dimensions
09-19-2007 · EurekAlert!
Brown University biomedical engineers have created a new method for growing cells in three dimensions rather than the traditional two. This 3-D petri dish allows cells to self-assemble, creating cell clusters that can be transplanted in the body or used to test drugs in the lab. This simple new technique is part of a growing body of research that shows that 3-D culture techniques can create cells that behave more like cells in the body.
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- Penn Veterinary Medicine report new strategy to create genetically-modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Two bacteria better than one in cellulose-fed fuel cell
07-27-2007 · EurekAlert!
No currently known bacteria that allow termites and cows to digest cellulose, can power a microbial fuel cell and those bacteria that can produce electrical current cannot eat cellulose. But careful pairing of bacteria can create a fuel cell that consumes cellulose and produces electricity, according to a team of Penn State researchers.
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- Putting stem cell research on the fast track
09-12-2007 · EurekAlert!
Engineers at Rensselaer Polytechnic Institute have developed tools to help solve two of the main problems slowing the progress of stem cell research -- how to quickly test stem cell response to different drugs or genes, and how to create a large supply of healthy, viable stem cells to study from only a few available cells.
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- Taxol bristle ball: a wrench in the works for cancer
09-12-2007 · EurekAlert!
Rice University chemists have discovered a way to load dozens of molecules of the anti-cancer drug Taxol onto tiny gold spheres. The result is a ball many times smaller than a living cell that literally bristles with the drug. Researchers hope to use the Taxol bristle ball to deliver large quantities of Taxol directly to cancer cells. The research will appear in the Sept. 19 issue of the Journal of the American Chemical Society.
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- Immune cell communication key to hunting viruses, Jefferson immunologists show
10-25-2006 · EurekAlert!
Immunologists have used nanotechnology to create a novel "biosensor" to solve in part a perplexing problem in immunology: how the immune system's killer T-cells hunt down invading viruses. They have found that surprisingly little virus can turn on killer T-cells, thanks to some complicated communication among "antigen presenting" proteins that recognize and attach to the virus, making it visible to the immune system. Presenting proteins cooperate, spreading a signal among receptors and boosting T-cell response.
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- MIT creates 3D scaffold for growing stem cells
12-27-2006 · Massachusetts Institute of Technology (MIT)
An MIT engineer and colleagues report that stem cells grew, multiplied and differentiated into brain cells on their new three-dimensional scaffold of tiny protein fragments designed to be more like a living body than any other cell culture system.
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- Penn scientists engineer small molecules to probe proteins deep inside cell membrane
03-30-2007 · EurekAlert!
To probe the secrets of inaccessible transmembrane proteins, researchers at the University of Pennsylvania School of Medicine have designed peptides that are able to bind to specific inner regions, using computer algorithms, and information from existing protein sequence and structure databases. This study looks at how the binding of these designed peptides affects the crucial first steps in blood clotting.
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