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A new significance of LVD and angiogenic MVD is identified in human primary SCRC
01-16-2008 · EurekAlert!A study led by Professor Xiang Du from Cancer Hospital, Fudan University, has investigated 132 cases with sporadic colorectal carcinoma and found that the detection of lymphatic vessel density and microvessel density at tumor borders may be useful in predicting metastasis and prognosis in patients with SCRC, and the co-accounting of LVD and MVD might be used as a prognostic factor of SCRC.
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Keywords: significance, lvd, angiogenic, mvd, identified, human, primary, scrc
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- Researchers discover new details about HIV-1 entry and infection
02-15-2007 · EurekAlert!
The primary targets of HIV-1 infection in the human vagina have been definitively identified in a new study published in the February 2007 issue of the journal Immunity, published by Cell Press. The findings are likely to guide development of new strategies that will prevent HIV-1 transmission.
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- Genes set scene for metastasis
04-11-2007 · EurekAlert!
Biologists at Memorial Sloan-Kettering Cancer Center have identified a set of genes expressed in human breast cancer cells that work together to remodel the network of blood vessels at the site of the primary tumor. These genes were also found to promote the spread of breast cancer to the lungs. The study, conducted in mice and reported in this week's Nature, helps to explain how cancer metastasis can occur and highlights targets for therapeutic treatment.
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- Window into human behavior, brain disease seen in UCSF study
12-22-2006 · EurekAlert!
UCSF scientists have identified a cell population that is a primary target of the degenerative brain disease known as frontotemporal dementia, which is as common as Alzheimer's disease in patients who develop dementia before age 65.
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- Study offers window into human behavior, brain disease
12-22-2006 · EurekAlert!
UCSF scientists have identified a cell population that is a primary target of the degenerative brain disease known as frontotemporal dementia, which is as common as Alzheimer's disease in patients who develop dementia before age 65.
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- Study links chemical to inhibited milk synthesis, secretion in humans
10-08-2007 · EurekAlert!
University of Cincinnati researchers have identified the neurotransmitter serotonin as the chemical responsible for inhibiting milk production and secretion in human mammary glands.
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- Study of successful drug targets could hasten development of new medications
02-01-2008 · EurekAlert!
Researchers from the University of Chicago Medical Center and Columbia University analyzed specific properties of the human genes and proteins that serve as targets for nearly a thousand FDA-approved drugs. They identified common characteristics of successful drug targets, especially those of high-revenue drugs. This data could speed up the process and cut down the cost of new drug development.
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- Nerve impulses from primary motor cortex can cause movement even when person is unaware
07-17-2007 · EurekAlert!
A new study identified the areas of the brain involved in both voluntary and involuntary movement and found that neural activity was restricted to the primary motor cortex during the unconscious motor activity seen with AHS.
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- Newly identified mechanism for silencing genes points to possible anti-cancer strategies
05-16-2007 · EurekAlert!
Scientists are only beginning to appreciate the extraordinary degree of control exercised over every step of the gene-to-protein production process. Only about 10 percent of human genes, for example, are active in a given cell at a given time, with the remaining 90 percent silenced by a various mechanisms. In a just-published study in Nature, scientists report an important new gene-silencing mechanism that points to promising potential targets for anti-cancer interventions.
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- Gene responsible for common hearing loss identified for first time
06-16-2007 · EurekAlert!
A gene responsible for the single most common cause of hearing loss among white adults, otosclerosis, has been identified for the first time, a scientist told the annual conference of the European Society of Human Genetics in Nice, France. Melissa Thys, from the Department of Medical Genetics, University of Antwerp, Belgium, said that this finding may be a step towards new treatments for otosclerosis, which affects approximately one in 250 people.
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- Human embryonic stem cells derived from preimplantation genetically diagnosed embryos
11-14-2007 · EurekAlert!
A human stem cell line derived from embryos that were identified by preimplantation genetic diagnosis to carry the mutation for fragile X syndrome has provided an unprecedented view of early events associated with this disease. In addition to giving scientists fresh insight into fragile X, results from this unique model system have emphasized the value of this new source of embryonic stem cells and may have a significant impact on the way that genetic diseases are studied in the future.
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