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Weill Cornell team discovers how brain's own tPA helps regulate blood flow to neurons
01-17-2008 · EurekAlert!The human brain contains its own store of a powerful enzyme (and stroke drug) called tissue plasminogen activator, which appears to be a key regulator of blood flow to brain cells, a team at the Weill Cornell Medical College in New York City reports.
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Keywords: weill, cornell, team, discovers, brain, tpa, regulate, blood, flow, neurons, discover, neuron
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01-29-2007 · EurekAlert!
Joslin researchers discover protein that causes blood vessel leakage and swelling in eyes with diabetic retinopathy. Discovery one day could lead to new treatments for eye diseases and brain swelling caused by head injury, stroke and other conditions.
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- A key enzyme helps keep the synapse on track
12-20-2007 · EurekAlert!
At its core, healthy neurological function hinges on the efficient passage of information between brain cells via the synapse. Figuring out how the synapse traffics this information -- a process called neurotransmission -- is crucial to understanding the function of the healthy and diseased brain. Now, a team led by researchers at Weill Cornell Medical College in New York City has spotted a crucial new piece to that puzzle.
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- Scientists identify brain abnormalities underlying key element of borderline personality disorder
12-20-2007 · EurekAlert!
Using new approaches, an interdisciplinary team of scientists at NewYork-Presbyterian Hospital/Weill Cornell Medical Center in New York City has gained a view of activity in key brain areas associated with a core difficulty in patients with borderline personality disorder -- shedding new light on this serious psychiatric condition.
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- Neuron cell stickiness may hold key to evolution of the human brain
11-02-2006 · EurekAlert!
The stickiness of human neurons may have been a key factor in why the human brain evolved beyond the brains of our primate relatives. In a study comparing the genomes of humans, chimpanzees and other vertebrates, researchers at the US Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) and Joint Genome Institute (JGI) found a strikingly high degree of genetic differences in DNA sequences that appear to regulate genes involved in nerve cell adhesion molecules.
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- Eltrombopag studied in Idiopathic Thrombocytopenic Purpura
11-28-2007 · EurekAlert!
There are estimated to be between 50,000-100,000 individuals in the US diagnosed with chronic Immune Thrombocytopenic Purpura, an autoimmune disease that dramatically reduces the number of platelets in their blood -- causing bruises, nosebleeds and, sometimes, life-threatening brain hemorrhages. Now, the results of an international multicenter clinical research study led by NewYork-Presbyterian Hospital/Weill Cornell Medical Center demonstrate that an investigational oral platelet growth factor called eltrombopag successfully increased platelet counts and decreased bleeding in patients with the condition.
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- Looking for something? Surprising number of neurons help find it, research shows
07-18-2007 · EurekAlert!
A person searching for a ripe tomato at the grocery store is more likely to notice apples, strawberries and other red fruits as well, according to a new study that measured changes in blood flow in the brain. The researchers also discovered that more neurons are called into action to help the eyes find a particular object than has previously been documented.
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- Pediatric ritalin use may affect developing brain, new study suggests
07-19-2007 · EurekAlert!
Use of the attention deficit/hyperactivity disorder (ADHD) drug Ritalin by young children may cause long-term changes in the developing brain, suggests a new study of very young rats by a research team at Weill Cornell Medical College in New York City.
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- Immune antibodies penetrate neurons to clear Alzheimer's-linked amyloid
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Researchers at Weill Cornell Medical College have gotten much closer to understanding how immune-based therapies can treat Alzheimer's disease -- by studying how antibodies go inside brain cells to reduce levels of Alzheimer's-linked amyloid peptides that form plaques between neurons.
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- Rutgers scientists discover brain cell development process implicated in mental retardation
07-31-2007 · EurekAlert!
Scientists at Rutgers University have discovered a biological process in brain cell development that may help explain some causes of mental retardation. This understanding may one day help other researchers develop therapies that can reduce specific forms of retardation. Proteins of the Rho family, when excessively present in developing brain cells known as neurons, inhibit another protein, called cypin, that promotes healthy neuron development.
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07-19-2007 · EurekAlert!
Challenging brain tissue with a small noxious stimulus beforehand gives it a resilience that can lessen damage to blood vessels during a stroke, report researchers at Weill Cornell Medical College in New York City.
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