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Genetic diversity of European Americans and disease gene mapping
01-17-2008 · EurekAlert!In a recent study, published in the open-access journal PLoS Genetics, an international team of researchers provide the first genetic dissection of the population structure of European Americans, focusing on identifying the contributions from different genetic ancestries that are important for disease gene mapping.
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Keywords: genetic, diversity, european, americans, disease, gene, mapping, american
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- Simulated populations used to probe gene mapping
03-23-2007 · EurekAlert!
Statisticians and genetic epidemiologists from Rice University and The University of Texas M. D. Anderson Cancer Center have used computer simulations to trace genetic changes over thousands of generations in a simulated population to find out whether the tools that statistical geneticists use to pinpoint disease genes are up to the task of identifying multiple genes that cause complex diseases like cancer. The study is published this week in PLoS Genetics.
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- Cedars-Sinai researchers on multicenter team linking gene mutation to Crohn's disease
10-26-2006 · EurekAlert!
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- After a decades-long search, scientists identify new genetic risk factors for multiple sclerosis
07-29-2007 · EurekAlert!
A pair of large-scale genetic studies supported by the National Institutes of Health has revealed two genes that influence the risk of getting multiple sclerosis -- data sought since the discovery of the only other known MS susceptibility gene decades ago. The findings could shed new light on what causes MS -- a puzzling mix of genes, environment and immunity -- and on potential treatments for at least 350,000 Americans who have the disease.
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- Secondhand smoke exposure worsens cystic fibrosis
01-29-2008 · EurekAlert!
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- Mexican Americans carrying haplotype H6 of the CYP2E1 gene have a greater risk of alcoholism
11-26-2007 · EurekAlert!
Mexican Americans make up 66 percent of the US Hispanic population and, when compared to other ethnic groups, show high rates of heavy drinking and alcohol-related problems. First-of-its-kind research that examines haplotypes -- clusters of genetic polymorphisms -- of the CYP2E1 gene among a Mexican-American population has found that carrying haplotype H6 may enhance susceptibility to developing alcoholism.
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A team of researchers has identified a new genetic mutation responsible for osteogenesis imperfecta (OI), a condition that makes bones much more likely to break, according to a study published today in the journal Cell. Victims may experience just a few fractures in a lifetime or several hundred beginning before birth. The number of Americans affected is unknown, but estimates range from 20,000 to 50,000.
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10-26-2006 · EurekAlert!
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A new study by York University biologists Amro Zayed and Laurence Packer has shown that a lone insect can initiate a biological invasion. Zayed, a recent graduate of Packer's lab, examined patterns of genetic diversity in both native European and invasive North American populations of a solitary bee. He concluded that the invasion was most likely founded by one mated female. The study is published in the open-access journal PLoS ONE.
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- UCLA scientists design masks to hide genetic mutations from cell
03-19-2007 · EurekAlert!
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07-18-2007 · EurekAlert!
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