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Genes linked with lupus are revealed, giving hope for new treatments
01-20-2008 · EurekAlert!Scientists have identified a number of genes involved in lupus, a devastating autoimmune disease, in new research published today in the journal Nature Genetics. In an international genetic study of more than 3,000 women, researchers found evidence of an association between lupus and mutations in several different genes.
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Keywords: genes, linked, lupus, revealed, giving, hope, treatments, gene, lupu, treatment
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- After a decades-long search, scientists identify new genetic risk factors for multiple sclerosis
07-29-2007 · EurekAlert!
A pair of large-scale genetic studies supported by the National Institutes of Health has revealed two genes that influence the risk of getting multiple sclerosis -- data sought since the discovery of the only other known MS susceptibility gene decades ago. The findings could shed new light on what causes MS -- a puzzling mix of genes, environment and immunity -- and on potential treatments for at least 350,000 Americans who have the disease.
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- Gene therapy offers new hope for treatment of peripheral neuropathy
05-31-2007 · EurekAlert!
Researchers from the University of Pittsburgh School of Medicine report that they have successfully used gene therapy to block the pain response in mice with neuropathic pain, a type of chronic pain in people for which there are few effective treatments. These findings are being presented at the 10th annual meeting of the American Society of Gene Therapy, being held May 30 to June 3 at the Washington State Convention & Trade Center, Seattle.
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- Gene mutations linked to hereditary lung disease
03-28-2007 · EurekAlert!
Scientists at Johns Hopkins have identified the genetic culprits that trigger a hereditary form of a fatal lung disease. The findings, published in the March 29, 2007, issue of the New England Journal of Medicine, may provide new directions in diagnosis and treatment for families that inherit genes for the disease, as well as for those that develop non-inherited forms of the illness.
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- Gene linked with childhood asthma is identified, giving hope for new therapies
07-04-2007 · EurekAlert!
A gene that is strongly associated with a risk of developing childhood onset asthma is identified in new research published online today in Nature.
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- 2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
04-12-2007 · EurekAlert!
Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
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- Massive microRNA scan uncovers leads to treating muscle degeneration
10-17-2007 · EurekAlert!
An increasing number of genes have been linked to muscular dystrophy and related disorders that cause muscle weakness and wasting, but it's still largely unknown how these genes cause disease, and, more importantly, how to translate the discoveries into treatments. A report in PNAS this week finds a wealth of new clues about how muscle function is regulated by analyzing microRNAs -- tiny bits of code that govern gene expression.
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- Dietary preferences and patterns may be linked to genes
06-07-2007 · EurekAlert!
Research indicates that the APOA2 gene is associated with food preferences and dietary patterns. About 15 percent of study participants had the genotype CC, which was linked to higher fat intake and almost two times the risk of obesity, as compared to people with more common genotypes of APOA2.
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- Genetic breakthrough offers promise in tackling kidney tumors
01-10-2008 · EurekAlert!
Early tests show promising results for a new treatment for tuberous sclerosis, which can cause tumors in organs throughout the body. The UK study is led by Cardiff University's Institute of Medical Genetics, which was the first to identify the genes linked to the disease.
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- Deep brain stimulation offers new hope for dystonia treatment
11-21-2006 · EurekAlert!
Dystonia, a group of diseases that cause a patient's muscles to involuntary contract with movement, has had a relatively limited and ineffective number of treatments in the past. New research shows that a recently developed surgical treatment, deep brain stimulation (an off switch for the brain), has provided dramatic benefits in some patients.
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- Jefferson scientists find aging gene also protects against prostate cancer development
11-27-2006 · EurekAlert!
Cancer researchers have found that a gene that is involved in regulating aging also blocks prostate cancer cell growth. They have shown that the enzyme SIRT1 can block the growth of treatment-resistant prostate cancer cells that overexpress a mutation for the androgen receptor. The scientists hope the newly found connection will aid in better understanding the development of prostate cancer and lead to new drugs against the disease.
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