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A new view of drugs used to treat rheumatoid arthritis

Powerful drugs used to treat patients with rheumatoid arthritis have a profound, previously unrecognized effect on the immune system, breaking up molecular "training camps" for rogue cells that play an increasingly recognized role in autoimmune diseases like rheumatoid arthritis and lupus.

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Keywords: view, drugs, used, treat, rheumatoid, arthritis, drug, arthriti

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1. TNF-alpha antagonist stops inflammation-induced colon cancer in its tracks
   01-24-2008 · EurekAlert!
   Individuals with the inflammatory bowel disease ulcerative colitis are at increased risk of developing colon cancer. New data have identified a central role for the soluble factor TNF-alpha in the development of colon cancer in mice induced to have inflammatory bowel disease. These data provide clear rationale for the idea that drugs antagonizing TNF-alpha (such as those used to treat rheumatoid arthritis) might reduce the risk of colon cancer in individuals with UC.
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2. Experimental MS drug shows promise, offers new window on disease
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3. Cancer Drug May Be Remedy For Rheumatoid Arthritis, Study Finds
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4. Annals of Internal Medicine tip sheet for March 20, 2007
   03-19-2007 · EurekAlert!
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5. Drug that lowers blood pressure might help prevent Alzheimer's disease
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6. Commonly used drug offers promise for premature babies
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   09-18-2007 · EurekAlert!
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8. A new target for the treatment of breast cancer
   01-11-2007 · EurekAlert!
   The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Berkeley Lab researchers have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation. TACE is strongly present in a form of breast cancer which responds poorly to current therapies.
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