Daily non-political popular news in brief.

Cigarettes leave deadly path by purging protective genes

01-23-2008 · EurekAlert!

A University of Rochester scientist discovered that the toxins in cigarette smoke wipe out a gene that plays a vital role in protecting the body from the effects of premature aging. Without this gene we not only lose a bit of youthfulness -- but the lungs are left open to destructive inflammation and diseases such as chronic obstructive pulmonary disease and lung cancer.

Keywords: cigarettes, leave, deadly, path, purging, protective, genes, cigarette, gene

« Previous | Next »

Similar news on "Cigarettes leave deadly path by purging protective genes":

Snake venoms share similar ingredients
12-19-2007 · EurekAlert!
Venoms from different snake families may have many deadly ingredients in common, more than was previously thought. A study published in the online open access journal BMC Molecular Biology has unexpectedly discovered three-finger toxins in a subspecies of the Massasauga Rattlesnake, as well as evidence for a novel toxin genes resulting from gene fusion.
Similar news · Read more »
Gene deficiency is a protective barrier to obesity
06-26-2007 · EurekAlert!
A search for the molecular clues of longevity has taken Mayo Clinic researchers down another path that could explain why some people who consume excessive calories don't gain weight. The study, which was done in laboratory mouse models, points to the absence of a gene called CD38. When absent, the gene prevented mice on high-fat diets from gaining weight, but when present, the mice became obese.
Similar news · Read more »
NEJM editorial on significance and limitations of new lupus gene expression research
01-20-2008 · EurekAlert!
This week marks a significant step forward in understanding how lupus works with the publication of four new studies identifying genes involved in this often debilitating chronic disease. In her editorial in the New England Journal of Medicine to accompany the papers, Hospital for Special Surgery Rheumatologist Mark K. Crow talks about the importance of the studies and the questions they leave unanswered, along with insights on next steps in lupus research.
Similar news · Read more »
Inhaling from just 1 cigarette can lead to nicotine addiction
07-03-2007 · EurekAlert!
A study published in the Archives of Pediatric and Adolescent Medicine shows that 10 percent of youth who become hooked on cigarettes are addicted within two days of first inhaling from a cigarette, and 25 percent are addicted within a month. The study's surprising findings are contrary to long-held beliefs that only people with established smoking habits of at least five cigarettes per day experience such symptoms.
Similar news · Read more »
Research linking Ashkenazi Jews & breast cancer genes beset by problems
11-01-2006 · EurekAlert!
Genetic research over the past decade has linked Ashkenazi Jewish ethnicity to an increased risk for hereditary breast cancer, so much so that certain gene mutations have become known as "Jewish ancestral mutations." But a new study released in the November 2006 issue of the American Journal of Public Health challenges this population-based approach, warning that disparities in access to care and other unintended consequences for specific ethic groups can result, and may have already occurred.
Similar news · Read more »
Sea urchin genome is a biology boon and a computational feat
11-09-2006 · EurekAlert!
Now that the entire DNA map of the sea urchin is complete, it's clear that these spiny sea creatures are even closer genetic cousins to humans than suspected. Brown University professors Gary Wessel and Sorin Istrail helped reveal the secrets of the urchin -- from its powerful immune system to its formidable gene regulatory network -- by identifying individual genes and creating the first high-resolution map of genes activated in its embryo. The work appears on the cover of Science.
Similar news · Read more »
AVN944 inhibits IMPDH and induces apoptosis-related biomarkers in patients with hematologic cancers
12-11-2006 · EurekAlert!
IMPDH is highly upregulated in most hematological cancers and solid tumors -- an essential role in cancer cell synthesis of DNA and RNA. Inhibition of IMPDH represents a new and important approach to treat cancer. In a Phase I trial of AVN944, AvalonRx identified a set of 34 genes. These gene markers correlate with the biochemical effects of AVN944 on protein function -- believed to result in tumor cell apoptosis at the right doses.
Similar news · Read more »
Researchers identify proteins involved in new neurodegenerative syndrome
08-15-2007 · EurekAlert!
The interplay of two proteins that bind to messenger RNA, a molecule that mediates translation of the information encoded in genes into proteins, triggers the appearance of fragile X-associated tremor/ataxia syndrome, a late-life disorder associated with the gene that causes fragile X syndrome in children, said researchers from Baylor College of Medicine in Houston and Emory University School of Medicine in a report that appears today in the journal Neuron.
Similar news · Read more »
Einstein researchers use novel approach to uncover genetic components of aging
08-24-2007 · EurekAlert!
People who live to 100 or more are known to have just as many -- and sometimes even more -- harmful gene variants compared with younger people. Now, scientists at the Albert Einstein College of Medicine of Yeshiva University have discovered the secret behind this paradox: favorable "longevity" genes that protect very old people from the bad genes' harmful effects. The novel method used by the researchers could lead to new drugs to protect against age-related diseases.
Similar news · Read more »
Gene profiling can single out the worst cases of multiple myeloma and guide therapy
09-18-2007 · EurekAlert!
Multiple myeloma patients vary widely in how they respond to treatment, but now researchers at the Myeloma Institute for Research and Therapy at the University of Arkansas for Medical Sciences have identified a small subset of genes whose activity could predict high-risk cases and potentially guide therapy in the future.
Similar news · Read more »