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Experimental procedure induces tolerance to mismatched kidney transplants

Four of five patients participating in a trial of an experimental protocol designed to induce immune tolerance to HLA-mismatched kidney transplants have been able to discontinue immunosuppressive drugs. The report in the Jan. 24 New England Journal of Medicine describes the first successful, intentional induction of tolerance across the HLA barrier in a group of transplant recipients.

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Keywords: experimental, procedure, induces, tolerance, mismatched, kidney, transplants, induce, transplant

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