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Building stronger bones, 1 stem cell at a time

Mesenchymal stem cells are capable of giving rise to various cell types through a process known as differentiation. A new study has determined that the anti-tumor drug bortezomib targets MSCs and leads to bone cell-specific differentiation. These data led the authors to suggest that Bzb might be a novel therapy for bone loss in individuals with osteoporosis and those with cancers accompanied by severe bone disease, such as myeloma.

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Keywords: building, stronger, bones, stem, cell, time, bone

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1. JCI table of contents: Jan. 24, 2008
   01-24-2008 · EurekAlert!
   This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published Jan. 24, 2008, in the JCI: TNF-alpha antagonist stops inflammation-induced colon cancer in its tracks; Building stronger bones, one stem cell at a time; Understanding a cause of Lou Gehrig’s disease; Genetic link to one form of a very common pediatric illness; and I can see clearly now Epo has come and gone.
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2. Type of stem cell found to reside in transplanted lungs
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3. Ireland Cancer Center researchers advance stem cell gene therapy
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4. A faster way to recover from chemotherapy and marrow transplant
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5. Smashing the time it takes to repair our bones
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8. BERT tells ERNI it's time to grow a brain
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