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TNF-alpha antagonist stops inflammation-induced colon cancer in its tracks

01-24-2008 · EurekAlert!

Individuals with the inflammatory bowel disease ulcerative colitis are at increased risk of developing colon cancer. New data have identified a central role for the soluble factor TNF-alpha in the development of colon cancer in mice induced to have inflammatory bowel disease. These data provide clear rationale for the idea that drugs antagonizing TNF-alpha (such as those used to treat rheumatoid arthritis) might reduce the risk of colon cancer in individuals with UC.

Keywords: tnf-alpha, antagonist, stops, inflammation-induced, colon, cancer, tracks, tnf, alpha, stop, inflammation, induced, track

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