Daily non-political popular news in brief.

Lungs' mast cells could provide new treatment target for asthma, other respiratory disease

An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.

Read more »

Keywords: lungs, mast, cells, provide, treatment, target, asthma, respiratory, disease, lung, cell

« Previous | Next »

Similar news on "Lungs' mast cells could provide new treatment target for asthma, other respiratory disease":

1. Cells in the lung clear the air to prevent lung damage
   03-01-2007 · EurekAlert!
   Air pollution and tobacco smoke contain oxidants that when inhaled can cause damage to the lungs and contribute to diseases such as asthma and chronic obstructive pulmonary disease (COPD). In a study that appears in the March issue of the Journal of Clinical Investigation, researchers from the Harvard School of Public Health, Boston, identify a new mechanism by which mice are protected against inhaled oxidants.
   Similar news · Read more »
   
2. Type of stem cell found to reside in transplanted lungs
   03-08-2007 · EurekAlert!
   A new study involving a type of stem cells from the lungs of transplant patients demonstrates for the first time that these progenitor cells reside in adult organs and are not derived from bone marrow, which leads to the possibility that the cells may be able to help with the rejection of donated organs and with various kinds of lung disease.
   Similar news · Read more »
   
3. Antioxidant protects against lung damage in silicosis
   10-16-2006 · EurekAlert!
   Levels of heme oxygenase-1 (HO-1), an antioxidant that protects against reactive oxygen species (damaging oxygen molecules that cause direct tissue injury), become elevated in the lungs of chronic silicosis patients and could represent a new treatment approach for the disease.These results appear in the second issue for October 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.
   Similar news · Read more »
   
4. Jefferson scientists find aging gene also protects against prostate cancer development
   11-27-2006 · EurekAlert!
   Cancer researchers have found that a gene that is involved in regulating aging also blocks prostate cancer cell growth. They have shown that the enzyme SIRT1 can block the growth of treatment-resistant prostate cancer cells that overexpress a mutation for the androgen receptor. The scientists hope the newly found connection will aid in better understanding the development of prostate cancer and lead to new drugs against the disease.
   Similar news · Read more »
   
5. Potential New Target For Leukemia Treatment
   10-10-2006 · ScienceDaily
   Cincinnati Children's Hospital Medical Center researchers have identified the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia. The paper is due to appear in an upcoming edition of the journal, Nature Immunology.
   Similar news · Read more »
   
6. Carbon monoxide protects lung cells against oxygen-induced damage
   01-18-2007 · EurekAlert!
   Researchers at the University of Pittsburgh have demonstrated that low-dose carbon monoxide administered in conjunction with oxygen therapy markedly inhibits oxygen-induced damage to lung cells. These findings, being reported in the January 19 issue of the Journal of Biological Chemistry, have significant implications for the treatment of acute respiratory distress syndrome, or ARDS, according to the study's authors.
   Similar news · Read more »
   
7. Penn study on lung-infecting bacterial enzyme suggests new approach to cystic fibrosis treatment
   04-18-2007 · EurekAlert!
   Researchers at the University of Pennsylvania School of Medicine have discovered that an enzyme produced by lung-infecting bacteria further shuts down a protein that is defective in cystic fibrosis patients. The disruption to this protein that conveys ions from lung cells to airways causes thick mucus to buildup inside the lung. The finding suggests a new therapeutic target for treating lung infections in some cystic fibrosis patients.
   Similar news · Read more »
   
8. Researchers identify protein pathway involved in Parkinson disease development
   06-18-2007 · EurekAlert!
   Scientists have found a novel signaling pathway in cells that is altered by genetic mutations recently identified in Parkinson disease development. These new findings show how the mutations affect cellular function and could provide a target for drug therapies to treat the disease.
   Similar news · Read more »
   
9. Rare lung disease cells indicate higher death risk
   01-16-2008 · EurekAlert!
   Large numbers of certain cells in the lungs of patients diagnosed with idiopathic pulmonary fibrosis may increase their chance of death, University of Cincinnati researchers have discovered.
   Similar news · Read more »
   
10. A PIN(1) prick for lung scarring: inhibiting PIN1 reduces rodent lung scarring
    01-10-2008 · EurekAlert!
    Chronic asthma often results in scarring of the lung airways (airway fibrosis) and this can cause airway obstruction. The soluble factor TGF-beta-1, produced by inflammatory cells known as eosinophils, drives the processes that cause airway fibrosis. New data, generated in rodents, has now led to the suggestion that targeting the protein PIN1 might provide a new approach to limiting airway fibrosis driven by the production of TGF-beta-1 by activated eosinophils in individuals with chronic asthma.
    Similar news · Read more »