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Researchers uncover more about how poxviruses evade the immune system
01-31-2008 · EurekAlert!Scientists at St. Louis University and the University of Alabama at Birmingham have uncovered important new information about a key protein that allows viruses such as smallpox to replicate and wreak havoc on the immune system.
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Keywords: researchers, uncover, poxviruses, evade, immune, system, researcher, poxviruse
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A team of researchers from the University of Pennsylvania School of Veterinary Medicine has identified the protein interactions involved in the immune system process that fights infection yet, in certain inflammatory diseases, runs amok and attacks friendly tissue.
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Tiny pieces of genetic material called microRNA could be key to HIV's ability to evade detection in the immune system. Researchers have shown that when an HIV-infected individual receives a powerful cocktail of antiviral agents called HAART, the virus uses miRNAs to help it hide and remain practically undetectable, temporarily shutting down its ability to replicate. Learning to manipulate miRNA's inhibitory effects might have implications for new strategies against the virus.
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- Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread
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- Poxvirus' ability to hide from the immune system may aid vaccine design
11-15-2007 · EurekAlert!
The cowpox virus, a much milder cousin of the deadly smallpox virus, can keep infected host cells from warning the immune system that they have been compromised, researchers at Washington University School of Medicine in St. Louis have found. The scientists also showed that more virulent poxviruses, such as the strains of monkeypox prevalent in Central Africa, likely have the same ability.
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- Potential New Target For Leukemia Treatment
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- Possible solution to Group B streptococci infection in newborn infants
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- Weak immune response critical to disease that causes most infant hospitalizations
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- LIAI scientists make important finding on cytomegalovirus transmission
05-10-2007 · EurekAlert!
Researchers at the La Jolla Institute for Allergy & Immunology have shown that cytomegalovirus (CMV) in the salivary glands can be reduced -- and in some cases eliminated -- through the use of antibodies to enhance the disease-fighting power of the immune system. The research team's findings, based on controlled laboratory studies of mice, may also have implications for other chronic virus infections, such as hepatitis and HIV, the virus that causes AIDS.
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