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Prostate cancer: Watchful wait or vaccinate?

Researchers at the University of Southern California have developed a prostate cancer vaccine that prevented the development of cancer in 90 percent of young mice genetically predestined to develop the disease. In the Feb. 1 issue of Cancer Research, they suggest the same strategy might work for men with rising levels of PSA, a potential diagnostic indicator of prostate cancer

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Keywords: prostate, cancer, watchful, wait, vaccinate

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1. Radiation seed implant decreases risk of death over watchful waiting
   10-31-2007 · EurekAlert!
   Prostate cancer patients cut their risk of dying of the disease in half when they receive radiation seed implants to treat their cancer, compared to those who don't receive active treatment, within six months from being diagnosed with localized prostate cancer, according to a study presented Oct. 31, 2007, at the American Society for Therapeutic Radiology and Oncology's 49th Annual Meeting in Los Angeles.
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2. Long-term financial costs associated with prostate cancer treatment
   12-21-2006 · EurekAlert!
   A new study reveals that the cumulative cost of prostate cancer is, on average, $42,570 over five years. Watchful waiting was the least expensive treatment while radiation and androgen deprivation therapy were the most expensive.
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3. Analysis: Older men treated for early prostate cancer
   12-12-2006 · EurekAlert!
   An analysis of Surveillance, Epidemiology and End Results-Medicare records for 44,630 older men suggests surgery or radiation therapy for early-stage prostate cancer increased the lifespan of men between 65 and 80 years old compared to observation, sometimes known as "watch and wait." The study supported a benefit of treatment even for men whose disease had a low risk of spreading, and even if they were elderly men (75 to 80 years old).
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4. Analysis: Older men treated for early prostate cancer live longer than those not treated
   12-12-2006 · EurekAlert!
   An analysis of Surveillance, Epidemiology and End Results-Medicare records for 44,630 older men suggests surgery or radiation therapy for early-stage prostate cancer increased the lifespan of men between 65 and 80 years old compared to observation, sometimes known as "watch and wait." The study supported a benefit of treatment even for men whose disease had a low risk of spreading, and even if they were elderly men (75 to 80 years old).
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5. PSA doubling predicts prostate cancer recurrence
   04-09-2007 · EurekAlert!
   A detectable level of prostate-specific antigen (PSA) is the first indicator of recurrent prostate cancer after radical prostatectomy. In a new Mayo Clinic study, the concept of PSA doubling time is found to be a reliable tool to distinguish which patients have prolonged innocuous PSA levels after therapy from those who are at great risk for disease recurrence and death from prostate cancer. Doubling time is defined as the duration for PSA levels in the blood to increase by 100 percent.
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6. New diagnostic technologies offer non-invasive means
   04-15-2007 · EurekAlert!
   Molecular messages and signals circulating in blood or contained in cells lining the airway can identify early stage cancer, according to research reported today at the 2007 Annual Meeting of the American Association for Cancer Research. Scientists looking to apply basic science knowledge to medical practice are developing tests that diagnose, predict or monitor cancer risks, without invasive tissue sampling. Such tests could benefit all, particularly underserved populations, such as the poor, who often wait until symptoms appear before seeing a doctor.
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7. New male sling procedure helps prostate cancer survivors who suffer from urinary incontinence
   08-29-2007 · UT Southwestern Medical Center
   Michael Yarborough, a 58-year-old business owner from Waxahachie, Texas, was fortunate. A routine check-up three years ago revealed prostate cancer, but a side effect of his successful surgery was "driving him nuts."
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8. Radiation therapy technique reduces length of prostate cancer treatment
   09-20-2007 · EurekAlert!
   Breihan Bridgewater suffers from emphysema. He sleeps on his side because when he lays flat on his back it feels like there's a boulder resting on his chest.
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9. Prostate cancer more likely to return in blacks than whites, but the disease is not more aggressive
   10-09-2007 · EurekAlert!
   African-American men are more likely to have their prostate cancer return after treatment, but their disease is no more aggressive when it does recur than that of their white counterparts, according to a study led by Duke Prostate Center researchers.
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10. Koch grant puts nanotechnology on front line of prostate cancer battle
    10-17-2007 · Massachusetts Institute of Technology (MIT)
    A $5 million grant from David H. Koch (S.B. 1962, S.M. 1963) will help researchers from several institutions, including MIT, develop nanotechnology to treat metastatic prostate cancer, for which there is no effective treatment.
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