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Taking more than 1 anti-inflammatory drug may lead to complications

02-01-2008 · EurekAlert!

A new study found that taking two NSAIDs was associated with lower scores on a health-related quality of life assessment.

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Keywords: taking, anti-inflammatory, drug, lead, complications, anti, inflammatory, complication

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  1. Non-steroidal anti-inflammatory drug increases liver damage in mice carrying mutant human gene
    11-15-2006 · EurekAlert!
    Research performed at Washington University School of Medicine in St. Louis sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug on liver injury.
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  2. Acute pancreatitis and cholangitis: a complication caused by a migrated gastrostomy tube
    10-25-2007 · EurekAlert!
    Percutaneous endoscopic gastrostomy is generally considered to be safe with a low rate of serious complications. However, dislocation of a gastrostomy tube can lead to serious complications. A research group led by Dr. Imamura experienced a very rare complication of acute pancreatitis and cholangitis caused by migrated gastrostomy tube. It is important to secure a PEG-tube at skin level, especially a couple of days after it is replaced.
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  3. White blood cell booster may help cancer patients avoid deadly complications
    07-25-2007 · EurekAlert!
    Cancer patients who receive a drug that stimulates the growth of infection-fighting white blood cells may be significantly less likely to die from a chemotherapy-related complication characterized by fever and low white blood cell levels, according to a multi-institutional study led by researchers from the University of Rochester School of Medicine and Dentistry and the Duke University Comprehensive Cancer Center.
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  4. MIT IDs mechanism behind fear
    07-15-2007 · EurekAlert!
    Researchers from MIT's Picower Institute for Learning and Memory have uncovered a molecular mechanism that governs the formation of fears stemming from traumatic events. The work could lead to the first drug to treat the millions of adults who suffer each year from persistent, debilitating fears -- including hundreds of soldiers returning from conflict in Iraq and Afghanistan.
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  5. The more we get, the more we need: Study shows how to prevent morphine 'tolerance'
    11-01-2007 · EurekAlert!
    Tolerance to the pain-relieving effects of morphine -- which builds rapidly with prolonged use -- can be prevented by blocking a substance that's formed when the drug is taken, researchers at Saint Louis University have discovered. Their findings could lead to new therapies that allow morphine to be administered without patients becoming tolerant of it -- a significant obstacle to effective pain relief -- nor experiencing a host of severe side effects that accompany escalating doses of the painkiller.
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  6. Monoclonal Antibody Reduces Exacerbations In Asthmatics, Study Finds
    10-10-2006 · ScienceDaily
    Patients with symptomatic moderate asthma who were treated with anti-tumor necrosis factor alpha, an anti-inflammatory monoclonal antibody, experienced significantly fewer disease exacerbations than individuals taking a placebo. This research appears in the first issue for October 2006 of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.
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  7. LIAI researchers identify a potential role for retinoic acid in autoimmune and inflammatory diseases
    06-14-2007 · EurekAlert!
    An important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others, was announced today by researchers at the La Jolla Institute for Allergy & Immunology. The studies, conducted in laboratory mice, demonstrated the role of retinoic acid, a substance derived when vitamin A is broken down in the body, in regulating inflammation.
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  8. Bariatric surgery complication rates high in some hospitals, new HealthGrades ratings and study show
    11-13-2006 · EurekAlert!
    In-hospital bariatric surgery complication rates vary dramatically among the nation's hospitals, according to a study released today by HealthGrades, the leading healthcare ratings company. The study of 86,520 bariatric-surgery procedures performed over the years 2002 through 2004 finds that a typical patient receiving the procedure in a five-star rated hospital would have, on average, a 66 percent lower chance of developing one or more major inhospital complications compared with a one-star rated hospital.
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    04-30-2007 · EurekAlert!
    Glucose homeostasis, the appropriate balancing of blood sugar levels, is impaired early in patients who become diabetic, causing life-threatening complications such as kidney failure and heart attacks. A study of the mechanisms of glucose homeostasis and early diabetes has dentified a key regulator of glucose homeostasis in humans.
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    06-29-2007 · EurekAlert!
    Acute mountain sickness affects almost half of those ascending to heights over 3,000 meters and may lead to life-threatening complications such as pulmonary or cerebral edema. A new study appearing in Journal of Travel Medicine details a prospective on-site study in the Himalayas between July and October 2004 in which the knowledge and practices concerning AMS were examined amongst trekkers.
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