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Genetic mutation increases risk of preterm birth

Genetic mutations in the Toll-like receptor 4 gene appear to have significant association with inflammatory injury to the placenta and developing baby, researchers from the University of Pittsburgh's department of obstetrics, gynecology and reproductive sciences report. "This indicates a possible genetic predisposition to a kind of misfire in immune system response that could contribute to placental inflammation and spontaneous preterm birth," researchers said.

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Keywords: genetic, mutation, risk, preterm, birth

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