Daily non-political popular news in brief.

Trainor Lab prevents rare birth defect by inactivating p53 gene

Using a mouse model of Treacher Collins syndrome, the Stowers Institute's Trainor Lab has demonstrated that it can prevent this rare disorder of craniofacial development either by inactivating a gene implicated in the abnormality or by inhibiting its protein product.

Read more »

Keywords: trainor, lab, prevents, rare, birth, defect, inactivating, p53, gene, prevent

« Previous | Next »

Similar news on "Trainor Lab prevents rare birth defect by inactivating p53 gene":

1. Repair of DNA by Brca2 gene prevents medulloblastoma
   05-18-2007 · EurekAlert!
   Investigators at St. Jude Children's Research Hospital have gained some of the first major insights into how certain genes known to prevent cancer also guide the normal development of the nervous system before birth and during infancy by repairing DNA damage.
   Similar news · Read more »
   
2. Bridging the Divide? Technique sheds light on cleft palate gene
   02-17-2007 · Science News Online
   A new approach has enabled researchers to prevent cleft palate in mice genetically engineered to develop that birth defect.
   Similar news · Read more »
   
3. Trainor Lab characterizes gene essential for prenatal development of nervous system
   02-01-2008 · EurekAlert!
   The Stowers Institute's Trainor Lab has demonstrated the role of a gene important to the embryonic development of the nervous system, a process that requires coordination of differentiation of immature neural cells with the cycle of cell division that increases their numbers. Until now, the mechanisms regulating these distinct cellular activities have been poorly understood.
   Similar news · Read more »
   
4. Scientists reveal secrets of Homer's Cyclops to help people with Holoprosencephaly
   01-17-2007 · EurekAlert!
   Scientists from Cleveland, Ohio, and Paris, France, reached an important milestone in understanding a molecular cause of a rare, but serious birth defect, Holoprosencephaly. In this February's FASEB Journal, researchers explain why and how some fetal brains fail to develop two lobes, as well as why and how the related skull and facial defects occur. Information from this study will enable researchers to pursue better approaches toward detecting, preventing, and treating this serious disorder.
   Similar news · Read more »
   
5. Rice breakthrough could prevent multiple fibrotic diseases
   01-18-2007 · EurekAlert!
   A scientific breakthrough at Rice University may lead to the first treatment that prevents the build-up of deadly scar tissue in a broad class of diseases that account for an estimated 45 percent of U.S. deaths each year. Fibrotic diseases include cardiac and pulmonary fibrosis, atherosclerosis, asthma, cirrhosis and scleroderma. Rice researchers have discovered a naturally occurring blood protein that's proven effective at preventing fibrotic scarring in lab animals.
   Similar news · Read more »
   
6. Gene-chip studies provide new leads in treating lung disease of premature newborns
   10-03-2007 · EurekAlert!
   Some 20 to 40 percent of extremely premature infants suffer abnormal lung development leading to bronchopulmonary dysplasia, a chronic lung disease that can cause long-term breathing problems. Little is known about how to predict whether a premature infant will develop BPD in the weeks after birth, much less how to prevent or treat it. Now, gene-chip studies of these tiny babies’ umbilical cords provide unexpected, much-needed leads into predicting and treating this debilitating condition.
   Similar news · Read more »
   
7. Gene involved in common birth defect also regulates skin biology
   10-15-2006 · EurekAlert!
   Following up on an earlier discovery that a gene called IRF6 is involved in the common birth defect cleft lip and palate, University of Iowa researchers and their colleagues have identified the function of the gene. Their latest findings, published online Oct. 15 in Nature Genetics, reveal an unexpected role for IRF6 in the growth and development of skin cells, a discovery that may have implications for wound healing and cancer research.
   Similar news · Read more »
   
8. New data reveal pregnancies exposed to accutane despite risk management program
   07-31-2007 · EurekAlert!
   More than 120 pregnancies were exposed during the first year of iPledge, a mandatory program designed to prevent pregnant women from being exposed to the anti-acne medication Accutane and similar medications containing isotretinoin (a known teratogen or birth defect-causing agent), a report revealed. The Food and Drug Administration's Dermatologic and Ophthalmic Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee will discuss the report's findings Aug. 1
   Similar news · Read more »
   
9. Cambridge led team discovers gene mutation which prevents carriers from feeling pain
   12-13-2006 · EurekAlert!
   Researchers have discovered a gene mutation which prevents the otherwise healthy carriers from sensing pain, after studying three related families with a rare genetic disorder in northern Pakistan.
   Similar news · Read more »
   
10. Rare mutation causes early heart disease and metabolic syndrome
    03-01-2007 · EurekAlert!
    Yale School of Medicine researchers have identified a rare defect in a single gene that poses a substantial risk for metabolic syndrome and early heart disease, the leading cause of death worldwide.
    Similar news · Read more »