Daily non-political popular news in brief.

Potential New Target For Leukemia Treatment

10-10-2006 · ScienceDaily

Cincinnati Children's Hospital Medical Center researchers have identified the crucial role and novel mechanism of action of the protein RhoH GTPase in the development and activation of cells critical to the immune system. The findings suggest that RhoH GTPase may provide a target for therapeutic intervention in some types of leukemia. The paper is due to appear in an upcoming edition of the journal, Nature Immunology.

Keywords: potential, target, leukemia, treatment

« Previous | Next »

Similar news on "Potential New Target For Leukemia Treatment":

Shilatifard and colleagues identify a potential target for treatment of mixed lineage leukemia
03-11-2007 · EurekAlert!
Ali Shilatifard, Ph.D., Investigator, has identified a cellular factor that can reverse histone trimethylation caused by the trithorax gene, the Drosophila homologue of the human mixed lineage leukemia gene, MLL. MLL, which is found in translocations in a variety of hematological malignancies, is a histone H3K4 methyltransferase.
Similar news · Read more »
Promising target for new atherosclerosis therapies linked to leukemia
11-01-2006 · EurekAlert!
In recent years, scientists studying inflammation and atherosclerosis have seen their respective fields converging, with research findings showing chronic inflammation as a driver of the atherosclerotic process. Now, in a new study, scientists at the Wistar Institute pursuing a promising new immune-system target for anti-atherosclerosis therapies have discovered another convergence: An unwanted potential side effect of any such therapies is a dangerous blood cancer called chronic myelogenous leukemia, or CML.
Similar news · Read more »
Liver fibrosis will be treated by a potential target
10-16-2007 · EurekAlert!
The hepatitis is either self recovery or its development into liver fibrosis or, further, liver cirrhosis. Since no ideal drug is available, liver fibrosis is currently considered to be a major worldwide health problem. A research conducted by by Dr. ZH Liu from Jilin University found that ARIP2 participates in the negative feedback regulation of signal transduction in the late stage by affecting the expression of ActRIIA, which further suggests that ARIP2 might be a potential target for treatment of liver fibrosis induced by activin.
Similar news · Read more »
JCI table of contents: Dec. 20, 2007
12-20-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published Dec. 20, 2007, in the JCI: "You can teach an old dog new tricks: antimalarial prevents cancer in mice"; "How an Atkins-like diet can treat epilepsy: Leptin attenuates rodent seizure severity"; "A new potential target in the treatment of a fatal brain disease"; "What AM I? AM is a regulator of vascular system functionality"; and others.
Similar news · Read more »
Discoveries thrust cancer-initiating stem cells into a larger role in cancer biology and treatment
04-18-2007 · EurekAlert!
Recent discoveries about the role of stem cells in cancer have altered the landscape of cancer research. With each new study, scientists are learning more about cancer-initiating properties of stem cells at organ sites and throughout the body. Increasingly, stem cells are examined as the cause -- and potential target of treatment -- for many, if not all, cancers.
Similar news · Read more »
Lungs' mast cells could provide new treatment target for asthma, other respiratory disease
01-29-2008 · EurekAlert!
An enzyme released by mast cells in the lungs appears to play a key role in the tightening of airways that is a hallmark of asthma -- pointing to a potential new target for treatment against the illness.
Similar news · Read more »
Massey researchers induce cell death in leukemia
04-16-2007 · EurekAlert!
Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia.
Similar news · Read more »
Alzheimer's enzyme acts as a tumor suppressor
06-07-2007 · EurekAlert!
Researchers at Burnham Institute for Medical Research ("Burnham") have provided the first evidence that gamma-secretase, an enzyme key to the progression of Alzheimer's, acts as a tumor suppressor by altering the pathway of epidermal growth factor receptor (EGFR), a potential treatment target for cancer. Expedited to publication online by Proceedings of the National Academy of Sciences, these findings reveal a limitation of targeting gamma-secretase for treatment of Alzheimer's and potentially other diseases.
Similar news · Read more »
Study identifies novel Parkinson's disease drug target
06-21-2007 · EurekAlert!
Researchers at the MassGeneral Institute for Neurodegenerative Disease (MGH-MIND) have identified a potential new drug target for the treatment of Parkinson's disease and possibly for other degenerative neurological disorders.
Similar news · Read more »
Jefferson scientists find protein potential drug target for treatment-resistant prostate cancer
12-31-2007 · EurekAlert!
Scientists at Jefferson's Kimmel Cancer Center in Philadelphia have found that a signaling protein that is key to prostate cancer cell growth is turned on in nearly all recurrent prostate cancers that are resistant to hormone therapy. If the findings hold up, the protein, called Stat5, may be a specific drug target against an extremely difficult-to-treat cancer.
Similar news · Read more »