Daily non-political popular news in brief.
Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells
02-05-2008 · EurekAlert!Researchers are identifying innovative therapeutics for sickle cell anemia that focus on specific factors in the disease's progression, such as the important role of hydration of the red blood cells. According to a study prepublished online in Blood, the official journal of the American Society of Hematology, a novel small molecule therapy called senicapoc showed efficacy in maintaining hydration of red blood cells and increasing hemoglobin levels in patients with sickle cell anemia.
Read more »
Keywords: novel, molecule, therapy, shows, benefit, anemic, patients, via, hydration, red, blood, cells, show, patient, cell
« Previous | Next »
Similar news on "Novel small molecule therapy shows benefit for anemic patients via hydration of red blood cells":
- Anticancer drugs might be of benefit to sickle-cell patients
12-06-2007 · EurekAlert!
Although some individuals with the inherited blood disorder sickle cell disease benefit from treatment with hydroxyurea, which increases fetal hemoglobin expression, it does not work for all sickle-cell patients. Now, hope for a new therapy has been provided by the observation that the anticancer drugs lenalidomide and pomalidomide were more effective than hydroxyurea at inducing HbF expression by red blood cells derived in vitro from CD34+ cells from both healthy and sickle-cell individuals.
Similar news · Read more »
- T vs. B: Re-engineered human T cells effectively target and kill cancerous B cells
09-18-2007 · EurekAlert!
Human white blood cells, engineered to recognize other malignant immune cells, could provide a novel therapy for patients with highly lethal B cell cancers such as acute lymphoblastic leukemia, according to researchers at Memorial Sloan-Kettering Cancer Center. By administering repeated doses of T cells designed to express an artificial receptor which recognizes human B cells, the researchers were able to eradicate cancer in 44 percent of mice bearing human ALL tumors.
Similar news · Read more »
- UF researchers test stem cell therapy for heart patients
10-04-2007 · EurekAlert!
University of Florida doctors treated the first patient in a new study to test whether a person's own stem cells can be used to restore blood flow to the heart by prompting new blood vessels to grow.
Similar news · Read more »
- Novel 3-D cell culture model shows selective tumor uptake of nanoparticles
08-23-2007 · EurekAlert!
A novel cell culture model consisting of an aggregate of brain tumor cells growing on normal thin slices of brain tissue has been developed to investigate tumor properties and therapy. The tumor cells showed a similar invasion pattern to that seen when growing in patients. When nanoparticles made from a new type of polymer were added to the co-culture, the nanoparticles were taken up more by the tumor cells than the normal brain cells.
Similar news · Read more »
- Exercise Helps Breast Cancer Patients Avoid Anemia
10-09-2006 · ScienceDaily
Women undergoing radiation treatment for breast cancer benefit from moderate intensity, regular aerobic activity, according to a new study. The study found that exercise improved the oxygen capacity of patients and maintained levels of red blood cells during radiation treatment.
Similar news · Read more »
- Better assessment of transfusions could save blood
02-06-2007 · EurekAlert!
Nearly 95 percent of patients admitted to hospital intensive care units are affected by anemia. Consequently, these patients receive a large number of red blood cell (RBC) transfusions in order to restore proper hemoglobin levels. New research shows that alternative treatments may lead to fewer transfusions, conserving critical blood supplies in hospitals. The report is published in Seminars in Dialysis.
Similar news · Read more »
- Unlocking proteins from their cellular shell
08-02-2007 · EurekAlert!
Applying physical stress to cells, researchers at the University of Pennsylvania have demonstrated that everyday forces can alter the structure of proteins tucked within cells, unfold them and expose new targets in the fight against disease.The findings for both simple red blood cells and more versatile stem cells show that hidden and folded parts of proteins can be exposed by physical strain. From there, proteins can be labeled and mapped, increasing the understanding of cellular behavior and unlocking novel targetable sites for drugs.
Similar news · Read more »
- Intravenous nanoparticle gene therapy shows activity in stage IV lung cancer
04-17-2007 · EurekAlert!
A cancer-suppressing gene has been successfully delivered into the tumors of stage four lung cancer patients via an intravenously administered lipid nanoparticle in a phase I clinical trial at the University of Texas M. D. Anderson Cancer Center. The gene, FUS1, also was found to be active in the metastatic nonsmall cell lung cancer tumors.
Similar news · Read more »
- Ireland Cancer Center researchers advance stem cell gene therapy
12-12-2007 · EurekAlert!
Ireland Cancer Center of University Hospitals Case Medical Center researchers recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects. This is the first time selection of this gene has been shown to occur in patients.
Similar news · Read more »
- Under magnetic force, nanoparticles may deliver gene therapy
07-31-2007 · EurekAlert!
After binding DNA segments to tiny iron-containing spheres called nanoparticles, researchers have used magnetic fields to direct the nanoparticles into arterial muscle cells, where the DNA could have a therapeutic effect. Although the research, done in cell cultures, is in early stages, it may represent a new method for delivering gene therapy to benefit blood vessels damaged by arterial disease.
Similar news · Read more »