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Scientists solve structure of gene regulator that plays key role in cancer

02-13-2008 · EurekAlert!

Scientists at the Wistar Institute have collaborated on a major advance in understanding a gene regulator that contributes to some of the deadliest cancers in humans. Their research paves the way for the development of new cancer therapies. The scientists have elucidated the 3-D structure of a key segment of p300/CBP, one of the most studied enzymes in the HAT family. Aberrant p300/CBP activity contributes to pancreatic, colon, and lung cancer and also can suppress tumors.

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Keywords: scientists, solve, structure, gene, regulator, plays, key, role, cancer, scientist, play

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