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NIH report on intracranial stent points out need for upcoming large-scale clinical trial
02-13-2008 · EurekAlert!A preliminary study funded by the National Institutes of Health found that a stent designed to open clogged arteries in the brain was successfully deployed in nearly all cases and significantly reduced arterial blockage in the short term. But data on the long-term benefit of the stent, compared to medical treatment alone, were inconclusive, prompting the upcoming launch of a large-scale randomized trial that is expected to provide definitive results.
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Keywords: nih, report, intracranial, stent, points, upcoming, large-scale, clinical, trial, point, large, scale
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- NIH announces phase III clinical trial of creatine for Parkinson's disease
03-22-2007 · EurekAlert!
The NIH National Institute of Neurological Disorders and Stroke today is launching a large-scale clinical trial to learn if the nutritional supplement creatine can slow the progression of Parkinson's disease (PD). While creatine is not an approved therapy for PD or any other condition, it is widely thought to improve exercise performance. The potential benefit of creatine for PD was identified by Parkinson's researchers through a new rapid method for screening potential compounds.
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- The Parkinson's Institute to conduct Phase III Clinical Trial of creatine for Parkinson's disease
03-22-2007 · EurekAlert!
The Parkinson’s Institute will participate in a large-scale national clinical trial to learn if the nutritional supplement creatine can slow the progression of Parkinson's disease (PD). The trial is sponsored by the National Institute of Health (NIH).
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- Story ideas from Molecular and Cellular Proteomics
01-22-2008 · EurekAlert!
Researchers have undertaken a large-scale investigation into the molecular environment of the amyloid precursor protein, a protein centrally associated with Alzheimer's disease. The variation in human platelets in the elderly population is not significantly large, report researchers in a study that has strong implications for clinical biomarker research.
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- Stem cell identity in culture may strongly depend on the cellular microenvironment
04-24-2007 · EurekAlert!
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology. In an upcoming PLoS ONE paper, researchers, including Andras Paldi, in Genethon (Evry, France) report, on the basis of experimental observations and computer simulations, that the stem cell identity in culture may strongly depend on the cellular microenvironment.
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- Herbal supplement fails to relieve hot flashes in large NIH trial
12-18-2006 · EurekAlert!
The herbal supplement black cohosh, whether used alone or with other botanical supplements, did not relieve hot flashes in postmenopausal women or those approaching menopause, who participated in the Herbal Alternatives (HALT) for Menopause Study, according to results from the clinical trial. The research, funded by the NIH, found that women using menopausal hormone therapy, however, did receive significant relief from their hot flashes and night sweats.
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- First large-scale HIV vaccine trial in South Africa opens
02-08-2007 · EurekAlert!
A large-scale clinical trial of a candidate HIV vaccine -- which previously showed promise in smaller studies in the United States and elsewhere -- has now opened in South Africa. The study plans to enroll up to 3,000 HIV-negative men and women, making it the largest African HIV vaccine trial to date.
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- Lupus in women: New genetic risk factors identified
01-20-2008 · EurekAlert!
An international consortium of clinical scientists and genomics experts, including researchers from the Montreal Heart Institute and Université de Montréal, have uncovered multiple new genetic risk factors for systemic lupus erythematosus, commonly known as lupus. The large-scale genomic study is the first of its kind to investigate the genetic basis of lupus.
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- NIAID DNA vaccine for H5N1 avian influenza enters human trial
01-03-2007 · EurekAlert!
The first human trial of a DNA vaccine designed to prevent H5N1 avian influenza infection began on December 21, 2006, when the vaccine was administered to the first volunteer at the National Institutes of Health (NIH) Clinical Center in Bethesda, MD. Scientists from the Vaccine Research Center (VRC) at the National Institute of Allergy and Infectious Diseases (NIAID), one of the NIH Institutes, designed the vaccine. The vaccine does not contain any infectious material from the influenza virus.
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- Rutgers biomaterial debuts in clinical trials of new stent
10-18-2007 · EurekAlert!
A revolutionary, new biomaterial, developed at the New Jersey Center for Biomaterials at Rutgers University, has moved from the lab bench to field testing in record time. This achievement, a product of a breakthrough methodology in biomaterials discovery, is the enabling technology behind a coronary stent undergoing its first-in-human clinical trial in Germany and in Brazil.
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- UCLA, Caltech chemists report important step toward building molecular computers
01-24-2007 · EurekAlert!
A team of UCLA and Caltech chemists reports in the January 25 issue of the journal Nature the successful demonstration of a large-scale (160 kilobit) memory device that stores information using reconfigurable molecular switches. This research represents an important step toward the creation of molecular computers that are much smaller and could be more powerful than today's silicon-based computers.
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