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Blinded by sFRP-1: A WNT signaling protein plays a key role in glaucoma

02-14-2008 · EurekAlert!

Increased pressure in the eye is a major risk factor for glaucoma, one of the main causes of visual impairment and blindness in the world. It is thought that impaired outflow of fluid from the eye causes glaucoma-associated increased pressure in the eye, and the authors of a new study have now shown that increased expression of the protein sFRP-1, an inhibitor of cell signaling through WNT proteins, seems to be responsible for this.

Keywords: blinded, sfrp-1, wnt, signaling, protein, plays, key, role, glaucoma, sfrp, play

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