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Defining cancer's genetic 'support network'
02-14-2008 · EurekAlert!Researchers at Duke University's Institute for Genome Sciences & Policy have developed a new method that essentially does for the genetic pathways underlying cancer what social networking web sites can do for people: It finds the connections among them.
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Keywords: defining, cancer, genetic, support, network
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- Evolution of human genome's 'guardian' gives people unique protections from DNA damage
01-16-2008 · EurekAlert!
Evolution has given humans unique protections through the p53 regulatory network -- so-called guardian of the genome -- against DNA damage that could cause cancer or genetic diseases, according to a study led by Cincinnati Children's Hospital Medical Center in the Jan. 22 Proceedings of the National Academy of Sciences. Rodents do not have these same protections, creating the need for additional considerations when interpreting studies in rodent models.
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- Support for chromosomal theory of cancer found in cancers' development of drug resistance
06-27-2007 · EurekAlert!
Most cancer researchers are convinced that cancer results from a handful of genetic mutations that kick a cell into uncontrolled growth. UC Berkeley genetics researcher Peter Duesberg disagrees, and finds support for his "chromosomal" theory of cancer in the development of drug resistance by many cancers. While his theory implies their is no magic bullet against cancer, it does provide ways to detect cancer at an early stage.
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- Should children be permitted to get genetic testing for BRCA 1/2 mutations?
01-15-2008 · EurekAlert!
It's an ethical dilemma with serious implications. Should children be tested for gene mutations that predispose them to developing breast cancer and/or ovarian cancer later in life? New research suggests the next generation of parents may support testing minors even when any steps to reduce that risk will be postponed until adulthood -- a finding that challenges current policies.
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- Computer tool helps pinpoint risky gene mutations
02-15-2007 · EurekAlert!
Certain cancer risks can be passed down through families, the result of tiny changes in a family's genetic code. But not all genetic changes are deadly. To help medical counselors and physicians identify the mutations that pose the greatest health risks, researchers have developed and validated a new computer tool.
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- Genetic pathways to curable and incurable forms of pancreatic cancer identified
03-12-2007 · EurekAlert!
The genetic sequence has been discovered that leads to a rare form of pancreatic ductal adenocarinoma.
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- Horvitz urges support for basic science
04-26-2007 · Massachusetts Institute of Technology (MIT)
H. Robert Horvitz, the David H. Koch Professor of Cancer Biology and recipient of the Nobel Prize, delivered the 35th annual Killian Award lecture April 24. Horvitz spoke on "Worms, Life and Death:В Cell Suicide in Development and Disease."
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- More Than Bit Players: Snippets of RNA might sway pancreatic cancer
05-05-2007 · Science News Online
Small pieces of genetic material called microRNA might provide a preview of pancreatic cancer's aggressiveness and offer targets for combating the usually deadly disease.
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- Decoding gene expression in cancer tumors using noninvasive imaging
05-21-2007 · EurekAlert!
By correlating images of cancerous liver tissue with gene expression patterns, a research team led by a radiologist at the University of California, San Diego School of Medicine has developed tools that may some day allow physicians to view a CT image of a cancer tumor and discern its genetic activity.
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- Study shows big power of small RNAs, not just proteins, in halting cancer
06-06-2007 · EurekAlert!
CSHL researchers have identified a family of micro RNAs that enable a known tumor suppressor network to fight cancer growth.
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- Aggressive therapy best for certain AML patients
08-01-2007 · EurekAlert!
A new study suggests that acute leukemia patients whose cancer cells show a genetic change that usually predicts a swift return of the disease following remission may remain disease-free longer when given aggressive therapy. The findings apply to people with acute myeloid leukemia whose cancer cells have normal-looking chromosomes and a gene mutation called MLL-PTD.
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