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Genetics a key factor in premature infants' devastating eye disease
11-22-2006 · EurekAlert!Genetics play a major role in predisposing infants to retinopathy of prematurity (ROP), a disease prevalent in premature infants that disrupts normal blood vessel development of the retina and can lead to blindness, researchers at Yale School of Medicine report in the November issue of Pediatrics.
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Keywords: genetics, key, factor, premature, infants, devastating, eye, disease, genetic, infant
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01-14-2007 · EurekAlert!
Variations in a gene known as SORL1 may be a factor in the development of late onset Alzheimer's disease, an international team of researchers has discovered. The genetic clue, which could lead to a better understanding of one cause of Alzheimer's, is reported in Nature Genetics online, Jan. 14, 2007, and was supported in part by the National Institutes of Health.
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- Scientists find new genes for Crohn's disease
04-15-2007 · EurekAlert!
A consortium of US and Canadian researchers is reporting in today's online issue of Nature Genetics that they have discovered several more genetic variations that are strongly linked to an increased risk for the disease. The discovery of these Crohn's disease-associated genetic variants has identified several key biological pathways that will be the focus of further research to understand how the debilitating inflammatory process is initiated and maintained in many cases of the disease.
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04-02-2007 · EurekAlert!
Researchers from Massachusetts General Hospital, in collaboration with scientists from the Genzyme Corporation, have identified a potential treatment for a chronic lung disease affecting premature infants. The scientists find that the activity of transforming growth factor-beta is elevated in the lungs of an animal model of bronchopulmonary dysplasia and that treatment with an antibody to TGF-beta decreased the growth factor’s activity and improved lung development.
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- Genes linked with lupus are revealed, giving hope for new treatments
01-20-2008 · EurekAlert!
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- Journal theme issue highlights advances in eye disease genetics
02-12-2007 · EurekAlert!
Research on the genetic basis of eye diseases is enabling rapid progress in the diagnosis and treatment of these conditions, according to a series of articles on ophthalmic genetics in the February issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
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Adult bone marrow stem cells may help cure certain genetic eye diseases, according to University of Cincinnati researchers.
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11-07-2007 · EurekAlert!
The brains of full-term infants with congenital heart disease appear more similar to those of premature newborns than to the brains of normal-term infants, a study conducted by researchers at UCSF has found. The study suggests that the mental and physical impairments in children with congenital heart disease may also have their origins in utero in addition to injuries resulting from surgery.
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In research supported primarily by the National Institutes of Health, scientists have discovered more than 25 genetic variants in 18 genes connected to cholesterol and lipid levels. Seven of the 18 genes previously had not been connected, while the 11 others confirm previous discoveries. The study will appear online Jan. 13 in Nature Genetics. These variants potentially open the door to strategies for the treatment and prevention of CAD.
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