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Living view in animals shows how cells decide to make proteins
11-30-2006 · EurekAlert!Scientists at Duke University Medical Center have visualized in a living animal how cells use a critical biological process to dice and splice genetic material to create unique and varied proteins.
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Keywords: living, view, animals, shows, cells, decide, make, proteins, animal, show, cell, protein
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11-03-2006 · EurekAlert!
A protein with the ironic name "Srcasm" can counteract the effects of tumor-promoting molecules in skin cells. Using animal models, the researchers discovered that Srcasm acts like a brake in epithelial cells, preventing uncontrolled cell growth caused by a family of proteins called Src kinases. This finding, published online in the Journal of Biological Chemistry, suggests a target for future gene therapy to treat skin, head, neck, colon and breast cancers.
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- Brain cell growth diminishes long before old age strikes, animal study shows
10-15-2007 · EurekAlert!
Soon after marmosets reach adulthood, the rate at which new neural cells form in the hippocampus region of the animals' brains begins to decline. The hippocampus is associated with both learning and memory. While similar observations have been made previously in the brains of rodents, this is the first time the decrease in new cell growth has been noted in a primate.
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09-05-2007 · EurekAlert!
A new mouse model for myotonic dystrophy - the most common form of adult-onset muscular dystrophy - helped Baylor College of Medicine researchers show that levels of CUGBP1, a protein that binds and controls the activity of the genetic material RNA, increase early in affected cells of the animals with the disease. This means CUGBP1 plays a key role in the disorder.
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- Scripps research scientists show protein accelerates breast cancer progression in animal models
06-20-2007 · EurekAlert!
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- Novel drug preventing protein recycling shows potential for treating leukemia
04-19-2007 · EurekAlert!
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found that a novel targeted therapy effectively treats acute leukemia in animal models by preventing cancer cells from being purged of damaged proteins.
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- Advance helps explain stem cell behavior
11-20-2006 · EurekAlert!
Biochemists at Oregon State University have developed a new method to identify the "DNA-binding transcription factors" that help steer stem cells into forming the wide variety of cells that ultimately make up all the organs and parts of a living vertebrate animal. The research is an important step towards understanding stem cell behavior and how cellular development is controlled.
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02-06-2007 · EurekAlert!
A new way to test the safety of the air we breathe is proving faster, cheaper and more humane than exposing laboratory animals to airborne chemical hazards, say UNSW scientists. Researchers at the university's Chemical Safety and Applied Toxicology Laboratories have developed an animal-free alternative that exposes living human cells to air pollutants inside a small chamber. The breakthrough could fast-track scientific understanding of the threat to human health posed by thousands of airborne chemical compounds.
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02-13-2007 · EurekAlert!
Biologists have discovered a new super-family of developmental proteins that are critical for cell growth and differentiation and whose further study is expected to benefit research on cancer and the nerve-cell repair. The protein super-family, which existed before the emergence of animals about 850 million years ago, is of major importance for understanding how life evolved in primordial times. The discovery will be described in the February 14, 2007 issue of the journal PLoS ONE.
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04-12-2007 · EurekAlert!
Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
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06-13-2007 · EurekAlert!
Researchers have discovered a molecular link between the cell's two major pathways for breaking down proteins and have succeeded in using this link to rescue neurodegenerative diseases in a simple animal model.
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