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Molecular 'marker' on stem cells aids research, perhaps therapies

12-04-2006 · EurekAlert!

A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.

Keywords: molecular, marker, stem, cells, aids, research, perhaps, therapies, cell, aid, perhap, therapy

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Molecular 'marker' on stem cells aids research, perhaps therapies
12-05-2006 · UT Southwestern Medical Center
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.
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AIDS interferes with stem cells in the brain
08-15-2007 · EurekAlert!
Scientists at the Burnham Institute for Medical Research have discovered how HIV/AIDS disrupts the normal replication of stem cells in the adult brain, preventing new nerve cells from forming. Drs. Stuart Lipton, Marcus Kaul, Shu-ichi Okamoto and colleagues uncovered a novel molecular mechanism that inhibits stem cell proliferation and that could possibly be triggered in other neurodegenerative diseases. These findings were published today online by the journal Cell Stem Cell.
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Diverse genetic abnormalities lead to NF-κB activation in multiple myeloma
08-13-2007 · EurekAlert!
Two new studies may lead to the development of more effective therapies for individuals with multiple myeloma, a common and incurable blood cell cancer. The research, published by Cell Press in the August issue of the journal Cancer Cell, provides new insight into the molecular mechanisms that underlie aberrant NF-κB activity in MM tumor cells and underscores the relevance of the signaling pathway as a target for MM therapy.
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Other highlights in the December 20 JNCI
12-19-2006 · EurekAlert!
Also in the December 20 issue of JNCI -- A report on breast cancer stem cells and radiation; research connecting statin use and advanced prostate cancer; a study of asthma medication and pancreatic cancer cell growth; and a model that predicts the risks of radiation therapy for leukemia patients.
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ESF EURYI award winner aims to stop cancer cells reading their own DNA
08-09-2007 · EurekAlert!
A promising new line in anticancer therapy by blocking the molecular motors involved in copying genetic information during cell division is being pursued by young Dutch researcher Dr. Nynke Dekker in one of this year's EURYI award winning projects sponsored by the European Science Foundation and the European Heads of Research Councils.
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New use for stem cells found in war on terrorism
09-25-2007 · EurekAlert!
For more than a decade, Steve Stice has dedicated his research using embryonic stem cells to improving the lives of people with degenerative diseases and debilitating injuries. His most recent discovery, which produces billions of neural cells from a few stem cells, could now aid in national security. In collaboration with the US Naval Research Laboratory, Stice hopes to use his recently developed neural cell kits to detect chemical threats.
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U of MN adult stem cell research shows promise for transplant therapies
01-15-2007 · EurekAlert!
University of Minnesota stem cell researchers, together with collaborators at Stanford University, have successfully used adult stem cells to replace the immune system and bone marrow of mice, offering the promise of new therapies for people in the future.
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First human trial tests stem-cell-based treatment for heart attacks
03-25-2007 · EurekAlert!
Previous research on the efficacy of stem cell therapy for heart repair has shown possible benefit from mesenchymal stem cells (MSCs) -- cells found in bone marrow that create connective tissue, bone and cartilage. A study presented today at the American College of Cardiology's Innovation in Intervention: i2 Summit reveals the results of the first human trial using MSCs for the treatment of myocardial infarction (MI, or heart attack).
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Ireland Cancer Center researchers advance stem cell gene therapy
12-12-2007 · EurekAlert!
Ireland Cancer Center of University Hospitals Case Medical Center researchers recently made great strides in stem cell gene therapy research by transferring a new gene to cancer patients, via their own stem cells, with the ultimate goal of being able to use stronger chemotherapy treatment with less severe side effects. This is the first time selection of this gene has been shown to occur in patients.
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Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
10-31-2007 · EurekAlert!
According to a new study, recently published in Circulation Research, a journal of the American Heart Association, University of Missouri-Columbia researchers have demonstrated that a muscular dystrophy patient should be able to maintain a normal lifestyle if only 50 percent of the cells of the heart are healthy.
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