Daily non-political popular news in brief.
Brown scientists map structure of DNA-doctoring protein complex
12-06-2006 · EurekAlert!Mobile DNA, which inserts foreign genes into target cells, is a powerful force in the march of evolution and the spread of disease. Working with the lambda virus and E. coli bacteria, Brown University biologists have solved the structure of a six-protein complex critical to performing this gene-grafting surgery. The technique they developed could be used to reveal the structure of other critical protein complexes, landing the work on the cover of Molecular Cell.
Read more »
Keywords: brown, scientists, map, structure, dna-doctoring, protein, complex, scientist, dna, doctoring
« Previous | Next »
Similar news on "Brown scientists map structure of DNA-doctoring protein complex":
- Man-made proteins could be more useful than real ones
02-06-2007 · EurekAlert!
Researchers have constructed a protein out of amino acids not found in natural proteins, forming a complex, stable structure closely resembling a natural protein. Their findings could help scientists design drugs that look and act like real proteins but won't be degraded by enzymes or targeted by the immune system, as natural proteins are.
Similar news · Read more »
- Scientists reveal structure of gateways to gene control
03-28-2007 · EurekAlert!
The first complete high-resolution map of structures that control how genes are packaged and regulated throughout an entire genome has been compiled by Penn State scientists. The research suggests how certain nucleosomes control whether a gene's function can be turned on. The study reveals an intimate relationship between the architecture of nucleosomes and the underlying DNA sequences they regulate, including a critical gateway that must be unlocked before a gene can be transcribed.
Similar news · Read more »
- Columbia scientists determine 3-dimensional structure of cell's 'fuel gauge'
02-08-2007 · EurekAlert!
Researchers at Columbia University Medical Center have uncovered the complex structure of a protein that serves as a central energy gauge for cells, providing crucial details about the molecule necessary for developing useful new therapies for diabetes and possibly obesity. A paper published online today in the journal Science details this structure, helping to explain one of the cell's most basic and critical processes.
Similar news · Read more »
- Researchers solve first structure of a key to intact DNA inheritance
12-20-2007 · EurekAlert!
Researchers have solved the structure of a DNA-protein complex that is crucial in the spread of antibiotic resistance among bacteria. Knowing this structure also provides fundamental insight into how cells successfully divide into two new cells with intact DNA
Similar news · Read more »
- Unique partnership produces life-critical 3D structures
03-28-2007 · EurekAlert!
Most diseases are caused by malfunctions in the body’s complex protein machinery. The next generation of drugs will be designed on the basis of 3D protein models that scientists are creating. The Structural Genomics Consortium laboratory at Karolinska Institutet in Sweden has now made available the structure of PARP3, the four hundredth structure in this unique project to chart the body’s proteins.
Similar news · Read more »
- Researchers reveal structure of protein altered in autism
06-12-2007 · EurekAlert!
As a result of mapping the structure of the protein complex implicated in autism spectrum disorders, a research team led by scientists at the University of California, San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences has discovered how particular genetic mutations affect this complex and contribute to the developmental abnormalities found in children with autism.
Similar news · Read more »
- Self-assembling nano-ice discovered at UNL -- Structure resembles DNA
12-11-2006 · EurekAlert!
UNL chemist Xiao Cheng Zeng and his team discovered double helixes of ice molecules that resemble the structure of DNA and self-assemble under high pressure inside carbon nanotubes. This discovery could have major implications for scientists in other fields who study the protein structures that cause diseases such as Alzheimer's and bovine spongiform ecephalitis. It could also help guide those searching for ways to target or direct self-assembly in nanomaterials.
Similar news · Read more »
- BCM, Rice scientists map flu's chemical key
10-15-2007 · EurekAlert!
Scientists from Baylor College of Medicine and Rice University have developed the first 3D, molecular map of the protein that allows influenza B to infect healthy cells with viral DNA. The research appears online this week in the Proceedings of the National Academy of Science. By studying influenza B, which affects only humans, researchers hope to shed light on the genetic mutations that would allow bird flu to spread among humans.
Similar news · Read more »
- Structure of iron regulatory protein-RNA complex solved
12-21-2006 · EurekAlert!
The surprising structure and properties of a protein responsible for regulating the transport, storage and use of iron -- as it binds its target RNA -- are described by researchers from the University of Illinois at Chicago in the December 22 issue of Science.
Similar news · Read more »
- New light-sensing ability discovered in disease-causing bacteria
08-23-2007 · EurekAlert!
The bacteria that cause brucellosis can sense light and use the information to regulate their virulence. The discovery comes after 120 years of research into the disease, which causes abortions in livestock and fevers in humans. Researchers found that two other bacteria, including a species that attacks plants, sense light using the same type of protein structure, and at least 94 more species possess the code for it in their DNA.
Similar news · Read more »
