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Study in the Journal of Clinical Pharmacology

Chemotherapy and radiation for the treatment of various malignancies often result in damage to mucus membranes. Patients suffer ulcerations, pain and an increase risk of infection. Palifermin is approved for use to decrease the chances of developing severe mucositis or injury to the cells lining the mouth, as well as shorten the time of severe mucositis in patients with cancer. Until, it hasn't been known whether patients with impaired kidney function required any different dosing.

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Keywords: study, journal, clinical, pharmacology

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