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Blood pressure drugs could help halt pancreatic cancer spread, Jefferson researchers find
12-07-2006 · EurekAlert!Common blood pressure medications might help block the spread of pancreatic cancer, researchers have found. The scientists showed in laboratory studies that two types of pressure-lowering drugs -- ACE inhibitors and AT1R blockers -- may help reduce the development of tumor-feeding blood vessels, a process called angiogenesis. Such drugs, they say, may become part of a novel strategy to control the growth and spread of cancer.
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Keywords: blood, pressure, drugs, halt, pancreatic, cancer, spread, jefferson, researchers, drug, researcher
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04-09-2007 · EurekAlert!
Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007, in the journal Proceedings of the National Academy of Sciences, could be a potential target for new drugs aimed at stopping or slowing the growth and progression of breast cancer.
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- Another 'smart' cancer drug can have toxic effects on the heart
12-13-2007 · EurekAlert!
Another FDA-approved targeted cancer drug, sunitinib, may be associated with cardiac toxicity, report researchers at Children's Hospital Boston, Dana-Farber Cancer Institute (Boston), and Thomas Jefferson University (Philadelphia). Sunitinib is one of several new "smart" cancer drugs called tyrosine kinase inhibitors that targets specific signaling molecules inside cancer cells that aid cancer spread, and was originally thought to be relatively free of cardiac side effects.
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- Researchers discover surprising drug that blocks malaria
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- Promising drug combination may help those with ocular melanoma that has spread
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01-10-2008 · EurekAlert!
A protein that helps prevent a woman's body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body. Researchers found that the metastatic pancreatic cancer cells in the lymph nodes produce enough of the protein, IDO, to wall-off the immune system's T-cells and recruit cells that suppress the immune response to the tumor.
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- Jefferson scientists find guardian gene's choices crucial to stopping cancer process
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