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Muscle and bone from an ink-jet printer

12-10-2006 · EurekAlert!

At the 2006 American Society for Cell Biology conference, scientists present the first research findings of a system that can pattern the formation of multiiple tissues from a single population of adult stem cells.

Keywords: muscle, bone, ink-jet, printer, ink, jet

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Pittsburgh-based team engineers muscle, bone cell differentiation with aid of ink-jet printer
12-10-2006 · EurekAlert!
A team of researchers from Carnegie Mellon University and the University of Pittsburgh has created and used an innovative ink-jet system to print "bio-ink" patterns that direct muscle-derived stem cells from adult mice to differentiate into both muscle cells and bone cells. The results, which could revolutionize the design of replacement body tissues, will be presented Sunday, Dec. 10 at the 46th annual meeting of the American Society for Cell Biology in San Diego.
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Testosterone replacement therapy: How safe for aging men?
08-08-2007 · EurekAlert!
Testosterone supplements have been used by aging men to improve their muscle mass, bone strength, libido and quality of life. The cardiovascular effects of chronic testosterone treatment in aging males are largely unknown, and the safety of testosterone replacement has not been evaluated. A team of researchers has been using an animal model to investigate potential links between testosterone supplements and cardiovascular and renal disease.
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Scientists discover new, readily available source of stem cells
01-07-2007 · EurekAlert!
Scientists have discovered a new source of stems cells and have used them to create muscle, bone, fat, blood vessel, nerve and liver cells in the laboratory. The first report showing the isolation of broad potential stem cells from the amniotic fluid that surrounds developing embryos was published today in Nature Biotechnology.
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Adult stem cell application effective in treatment of peripheric vascular disease
01-24-2008 · EurekAlert!
Multipotent adult progenitor stem cells extracted from bone marrow, and known as MAPCs, have proved to be effective in the regeneration of blood vessel tissue and also in muscle tissue when treating peripheric vascular disease.
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Certain diseases, birth defects may be linked to failure of protein recycling system
12-20-2007 · EurekAlert!
A group of signaling proteins known as Wnt -- which help build the human body's skin, bone, muscle and other tissues -- depend on a complex delivery and recycling system to ensure their transport to tissue-building cell sites. Failure of this system may be a mechanism of cancer, heart disease or birth defects related to Wnt proteins, according to researchers at Cincinnati Children's Hospital Medical Center.
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Life in Print
01-26-2008 · Science News Online
Tissues printed with an ink-jet could provide patches for damaged organs, new cell-based materials for drug testing, new ways to probe cellular communication, living sensors, or even fuel cell–type batteries.
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How to grow muscle cells in a dish
11-09-2006 · EurekAlert!
Smooth muscle cells (SMCs) are a crucial component of many parts of the body, including blood vessels. A new study shows that fully functional SMCs can be generated from multipotent adult progenitor cells (MAPCs) from rat, mouse, pig and human bone marrow using only the soluble factor TGF-beta or TGF-beta and PDGFB. SMCs generated this way could provide a source of SMCs for engineering tissues, for example new blood vessels for use in bypass surgery.
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Childhood cancer survivors at increased risk of sarcoma
02-20-2007 · EurekAlert!
Survivors of childhood cancers have a ninefold increased risk of developing a secondary sarcoma -- a cancer of connective or supportive tissue such as bone, fat, or muscle -- compared with the general population, according to a study in the February 21 Journal of the National Cancer Institute.
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Study helps explain origins of cardiac fibrosis in patients with heart disease
07-29-2007 · EurekAlert!
A report led by researchers at Beth Israel Deaconess Medical Center (BIDMC) helps explain the origins of cardiac fibrosis, a stiffening of the heart muscle that leads to a variety of cardiac diseases, most notably heart failure. The animal study, which appears today in the Advance Online Publication of Nature Medicine, also demonstrates that a bone morphogenic molecule known as rhBMP7 can reverse the cardiac fibrosis process, offering the possibility of a therapeutic target for this debilitating condition.
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Varying weight training intensity increases growth hormone in women
12-01-2006 · EurekAlert!
Women who undertake a long-term weight training program produce more biologically active growth hormone, a finding that allows physiologists to understand why weight training improves muscle tone and optimizes metabolic function. The study found that growth hormone was responsive to moderate and heavy exercise regimens having 3-12 repetitions with varying weight loading, suggesting women need to have heavy loading cycle or workout in their resistance training routines, as it helps to build muscle and bone.
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