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Drug combination proves effective against myeloma in Phase I trial
12-11-2006 · EurekAlert!Two "new generation" drugs for the bone marrow cancer multiple myeloma may work even better together than they do individually, according to the results of a multicenter Phase I clinical trial to be presented by Dana-Farber Cancer Institute scientists at the annual meeting of the American Society of Hematology in Orlando, Fla.
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Keywords: drug, combination, proves, effective, myeloma, phase, trial, prove
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- Drug combination slows progression of treatment resistant bone marrow cancer
12-12-2006 · EurekAlert!
Combining a newly formulated drug with one that is already a standard treatment slows the progression of multiple myeloma, an advanced cancer of the bone marrow cells, according to a clinical trial led by a University of North Carolina at Chapel Hill School of Medicine researcher.
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- Catalyst Pharmaceutical Partners Announces Positive Phase II Trial Results for Vigabatrin in the Treatment of Cocaine Addiction
12-07-2007 · Brookhaven National Laboratory
Catalyst Pharmaceutical Partners, Inc. (Nasdaq: CPRX), a biopharmaceutical company that acquires, in-licenses, develops and commercializes prescription drugs for the treatment of drug addiction, today announced positive initial top-line results from an investigator-initiated Phase II double-blind, placebo-controlled trial, which demonstrates that vigabatrin is effective for the treatment of cocaine addiction. Catalyst's lead compound, CPP-109, is bioequivalent to vigabatrin.
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- Penn's Abramson Cancer Center part of major phase III study for myeloma
11-21-2007 · EurekAlert!
Researchers from the UPenn's Abramson Cancer Center announced today that findings from two international clinical trials show unprecedented survival for patients with myeloma, a cancer the blood-making cells of bone marrow. Findings show that with the oral drug lenalidomide, in combination with dexamethasone, patients significantly improved by all measures where previous treatments had failed -- including a median survival of nearly three years -- the longest median survival known for this difficult to treat patient group.
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- Drug combination effective against multiple myeloma, researchers show
11-21-2007 · EurekAlert!
Pairing a new thalidomide derivative with a steroid slows progress of multiple myeloma, an incurable bone marrow cancer, and prolongs the lives of patients who have relapsed from previous treatment, researchers report in the Nov. 22 New England Journal of Medicine.
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- Acrux announces positive clinical trial resultswith combination contraceptive sprays
07-03-2007 · EurekAlert!
Acrux, the Australian drug delivery company, today announced positive results from its Phase 1 clinical studies using two unique contraceptive skin sprays, each containing a progestin and an estrogen.
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A combination of two medicines that act against the effects of the enzyme renin are more effective in lowering blood pressure than either of the medicines alone, according to a study presented today at the American College of Cardiology’s 56th Annual Scientific Session.
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- ZOLINZA (vorinostat) in combination with bortezomib demonstrated clinical activity
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Results from two investigational Phase I trials of ZOLINZA (vorinostat) in combination with bortezomib provide preliminary anti-tumor activity in patients with relapsed and/or refractory multiple myeloma.
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- High blood pressure medication strategy proves effective in Hispanic women
07-12-2007 · EurekAlert!
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- Phase I study of novel gene therapy for HIV
11-06-2006 · EurekAlert!
The results are in for Phase I clinical trials of a gene therapy for AIDS. The trial was conducted at U-Penn where five patients with chronic HIV who had failed prior therapies were given a one-time infusion. They all tolerated the therapy and showed improved immune system response. This is the first publication of an effective gene therapy for AIDS to show positive clinical results in the peer review literature.
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