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Mayo Clinic -- Collaborating to move treatment research forward

Novel therapies are greatly improving the long-term outlook for patients with multiple myeloma, say researchers at Mayo Clinic Cancer Center, who have led efforts in testing these treatments and moving them quickly into first-line therapies.

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1. Research shows new therapy is effective for patients with Crohn's disease
   07-18-2007 · EurekAlert!
   Mayo Clinic researchers have found that Certolizumab pegol is an effective treatment for adults with Crohn's disease, according to two new studies. These findings were published in today's issue of the New England Journal of Medicine. Certolizumab pegol blocks tumor necrosis factor, an important cause of inflammation in Crohn's disease
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2. New research may lead to earlier diagnosis and treatment of primary biliary cirrhosis in families
   09-10-2007 · EurekAlert!
   Mayo Clinic researchers have found that first-degree relatives (i.e., parents, siblings, children) of patients with primary biliary cirrhosis are more likely to have the biomarker of the disease in their blood. Armed with this new information, physicians could screen and assess first-degree relatives of PBC patients with a simple blood test, enabling them to diagnose and treat more patients before the disease causes irreversible liver damage. These findings were published in this month's issue of Hepatology.
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3. Benefits of testosterone treatment unknown, research shows
   01-09-2007 · EurekAlert!
   Little research exists demonstrating that testosterone is both safe from the cardiovascular standpoint and effective to treat sexual dysfunction, reveal Mayo Clinic researchers in two new studies.
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4. Brief, High-dose Steroid Treatment Offers Extended Relief To Giant Cell Arteritis Patients
   10-10-2006 · ScienceDaily
   A new study offers both hope and a practical treatment option for patients with giant cell arteritis (GCA). Researchers from Emory University and the Mayo Clinic have found that by treating newly diagnosed GCA patients with just three days of a high-dose intravenous steroid, patients relapsed less in the following year and were able to significantly taper off usage of an oral steroid.
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5. Mayo Clinic Cancer Center collaborating to find new tools to fight leukemia
   12-10-2006 · EurekAlert!
   Mayo Clinic Cancer Center, working in collaboration with Ohio State University Comprehensive Cancer Center, presented evidence Sunday that a novel regimen of three chemotherapy drugs, pentostatin, cyclophosphamide and rituximab, resulted in significant clinical response in patients with previously untreated chronic lymphocytic leukemia (CLL).
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6. Mayo Clinic research shows young people who died suddenly and inexplicably had genetic heart defects
   01-30-2007 · EurekAlert!
   Young people who died suddenly and inexplicably had genetic heart defects.
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7. First step in developing heart hormone-based pill to control high blood pressure
   03-27-2007 · EurekAlert!
   In an era of increasing death and illness from heart and blood vessel disease -- which also can impair kidney function -- Mayo Clinic researchers have designed two promising new cardiovascular treatment approaches.
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8. Mayo Clinic researchers find evidence for traumatic cause of carpal tunnel syndrome
   11-09-2006 · EurekAlert!
   New Mayo Clinic research suggests that a shearing injury of the tissue that lines the tendons within the carpal tunnel may cause carpal tunnel syndrome, a debilitating condition of the wrist and hand.
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9. Cryoablation -- A new treatment option for some kidney tumor patients
   03-28-2007 · EurekAlert!
   Mayo Clinic researchers report that freezing kidney tumors through percutaneous cryoablation shows promise for patients who are not good candidates for surgery.
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10. Oncolytics Biotech, Inc. announces publication of research
    01-07-2008 · EurekAlert!
    Dr. Richard Vile and his research team at the the Mayo Clinic College of Medicine in Rochester, Minn., has published the results of its work testing the antitumor efficacy and safety of various combinations of reovirus and cyclophosphamide in vivo. The paper, entitled "Cyclophosphamide Facilitates Antitumor Efficacy against Subcutaneous Tumors following Intravenous Delivery of Reovirus" appears online in the Jan. 1, 2008 issue of Clinical Cancer Research.
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