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Drug that chokes off tumor blood vessels offers new hope to lung cancer patients
12-13-2006 · EurekAlert!Patients suffering from the most common type of lung cancer experienced a 20-percent improvement in overall survival in a national clinical trial of a drug that chokes off the blood vessels nourishing tumors, a multicenter study has found.
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- Drug that chokes off tumor blood vessels offers new hope to lung cancer patients
12-14-2006 · UT Southwestern Medical Center
Patients suffering from the most common type of lung cancer experienced a 20-percent improvement in overall survival in a national clinical trial of a drug that chokes off the blood vessels nourishing tumors, a multicenter study has found.
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- Drug combination might offer hope for patients deadly brain tumors
10-18-2007 · EurekAlert!
Brain cancer patients with the poorest prognosis -- those with a type of deadly tumor known as glioblastoma multiforme -- may survive longer with a drug that chokes off a tumor's blood supply.
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- Blood-vessel blocker aids cancer-killing virus
11-27-2007 · EurekAlert!
Cancer-killing viruses are a promising therapy for incurable brain tumors, but their effectiveness has been limited in part because immune cells rapidly eliminate them. That immune response might be slowed, and the virus given more time to kill cancer cells, by blocking the growth of blood vessels in the tumor, new Ohio State research suggests. The study indicates that pretreatment with a drug that blocks blood-vessel growth might improve the effectiveness of cancer-killing viruses.
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- Novel method enables genomic screening of blood vessels from patient tissue
08-28-2007 · EurekAlert!
Scientists have developed a new method of capturing a complete genome-wide screening of blood vessel cells in their actual disease state, advancing the potential for genetic research on the tissue responsible for delivering nourishment that can accelerate the growth of both a cancer tumor or wound healing.
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- Jefferson scientists find blood vessel-building protein halts blood vessels from forming in cancer
11-14-2006 · EurekAlert!
A piece of the protein cellular scaffolding involved in building blood vessels duringdevelopment might have the opposite effect in tumors. Scientists have found that the protein fragment endorepellin blocks both skin and lung cancer tumors from progressing in animal models by preventing their ability to recruit new blood vessels, a process called angiogenesis. The researchers believe the finding could lead to a new type of tumor inhibitor to prevent cancer from spreading.
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- UCLA researchers discover biomarkers that predict lung cancer patient response to therapy
01-31-2008 · EurekAlert!
Researchers at UCLA's Jonsson Cancer Center have discovered biomarkers that predict which patients with advanced non-small cell lung cancer will respond to a combination treatment of the anti-inflammatory drug Celebrex and the growth factor receptor blocker Tarceva.
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- Targeting surgar on blood vessels may inhibit cancer growth
05-07-2007 · EurekAlert!
In a study that could point to novel therapies to prevent cancer spread, or metastasis, researchers at the University of California, San Diego, School of Medicine have targeted a sugar that supports blood vessel growth in the tumor. Their findings will be published in the May 7 online issue of Journal of Cell Biology.
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- Mouse tests predict drug response in relapsing pancreatic cancer patients
10-11-2006 · EurekAlert!
By slicing up bits of patient tumors and grafting them into mice, Johns Hopkins Kimmel Cancer Center specialists have figured out how to accurately "test drive" chemotherapy drugs to learn in advance which drug treatments offer each individual pancreatic cancer patient the best therapeutic journey.
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- Cancer treatment targets tumor blood supply in patients
03-02-2007 · EurekAlert!
An antibody called J591 specifically targets an antigen found in high amounts on both prostate tumors and on blood vessels of all solid tumors, according to a study by researchers at NewYork-Presbyterian Hospital/Weill Cornell Medical Center.
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- Study produces conflicting findings on the use of anti-anemia drug in cancer patients
04-16-2007 · EurekAlert!
Results from a phase III drug trial indicate that an anti-anemia drug did not significantly decrease the need for blood transfusions in patients not on chemotherapy, and decreased overall patient survival when compared to placebo, according to researchers from the UCLA Medical Center at the 2007 Annual Meeting of the American Association for Cancer Research.
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