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Profiling of cancer genes may lead to better and earlier detection

12-25-2006 · EurekAlert!

A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers -- lung, breast, prostate and colon cancer.

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Keywords: profiling, cancer, genes, lead, earlier, detection, gene

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Similar news on "Profiling of cancer genes may lead to better and earlier detection":

  1. Profiling of cancer genes may lead to better and earlier detection of solid human cancers
    12-27-2006 · UT Southwestern Medical Center
    A research team at UT Southwestern Medical Center has for the first time identified several genes whose expression is lost in four of the most common solid human cancers — lung, breast, prostate and colon cancer.
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  2. Data presented at ISHLT meeting confirm RNA analysis can identify rejection in lung transplant recip
    04-27-2007 · EurekAlert!
    Recent data from the Lung Allograft Rejection Gene expression Observational study provides compelling evidence that profiling gene expression in peripheral blood can detect organ rejection in lung transplant patients. Refining the Identification of Discriminatory Genes for Rejection in Lung Transplantation: The LARGO Study will be presented today by Shaf Keshavjee, M.D., chair, Division of Thoracic Surgery, University of Toronto, and LARGO study lead, at the 27th annual Meeting and Scientific Sessions of the International Society for Heart and Lung Transplantation.
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  3. Selective marker found to indicate aggressive form of breast cancer
    01-15-2007 · EurekAlert!
    Researchers have linked a structural protein called nestin to a particularly deadly form of breast cancer, identifying a new biomarker that could lead to earlier detection and better treatment.
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  4. Fat kills cancer
    07-03-2007 · EurekAlert!
    Researchers in Slovakia have been able to derive mesenchymal stem cells from human adipose, or fat, tissue and engineer them into "suicide genes" that seek out and destroy tumors like tiny homing missiles. This gene therapy approach is a novel way to attack small tumor metastases that evade current detection techniques and treatments, the researchers conclude in the July 1 issue of Cancer Research, a journal of the American Association for Cancer Research.
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  5. Prenatal arsenic exposure can alter genes
    11-22-2007 · Massachusetts Institute of Technology (MIT)
    The children of mothers whose water supplies were contaminated with arsenic during their pregnancies harbored gene expression changes that may lead to cancer and other diseases later in life, MIT researchers reported in a new study.
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  6. 2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
    04-12-2007 · EurekAlert!
    Individuals who inherit one mutant copy of any one of about 12 genes that make the proteins of the Fanconi Anemia pathway are at increased risk of developing cancer. This occurs when the remaining "good" copy of the gene becomes mutated in a specific cell type. However, hope of a new treatment for these cancers has now been provided by a new study indicating that inhibiting the protein ATM can kill these cancer cells.
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  7. Jefferson scientists see breast cancer gene activity from outside the body
    11-28-2007 · EurekAlert!
    Researchers at Jefferson Medical College and Jefferson's Kimmel Cancer Center in Philadelphia have used PET imaging to see hyperactive cancer genes inside breast tumors in laboratory animals, marking the first time such gene activity has been observed from outside the body. This technology might someday help physicians to detect and classify cancer, enabling them to find cancerous breast tumors as early as possible, and determine the appropriate treatment.
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  8. 10 Top Australian Scientists Predict Major Medical Advances
    10-10-2006 · ScienceDaily
    Australians will soon be able to find out how good their genes are at fighting disease, what risks they are susceptible to and what they can do to prevent ill-health. And by the turn of the century it will be commonplace to have a bad combination of genes repaired to avoid disease. A new report compiled by Research Australia with 10 top Australian medical researchers predicts individual gene profiling will revolutionize health care within a decade.
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  9. Genes and stressed-out parents lead to shy kids
    03-02-2007 · EurekAlert!
    New research in Current Directions in Psychological Science shows that shyness in kids could relate to the manner in which a stress-related gene in children interacts with being raised by stressed-out parents.
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  10. How mammals fuel milk production may have implications for cancer
    12-05-2006 · EurekAlert!
    In a new study in the December issue of the journal Cell Metabolism, published by Cell Press, the researchers found that one of three "isoforms" of the gene known as Akt is specifically required for lactating mice to synthesize sufficient quantities of milk to support their offspring. While the loss of so-called Akt1 does not lead to structural abnormalities, they found, mothers deficient for the gene exhibit a disruption of the coordinated metabolic changes that normally occur at the onset of lactation.
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