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Wound botulism

In a case study in PLoS Medicine, doctors report on the case of a 35-year-old heroin user who came to the accident and emergency department with double vision, slurred speech, drooping eyelids and eye muscle weakness. The diagnosis turned out to be wound botulism. Wound botulism is a potentially fatal illness that occurs when spores of the bacterium Clostridium botulinum contaminate a wound, germinate and produce botulimum nerve toxin.

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Similar news on "Wound botulism":

1. Highly concentrated botulinum preparation for cosmetic injections can result in severe illness
   11-21-2006 · EurekAlert!
   An examination of four cases of botulism following cosmetic injections to the face indicates that the adults received a highly concentrated, unlicensed preparation that resulted in toxin levels up to 40 times the estimated human lethal dose, according to a report in the Nov. 22/29 issue of JAMA.
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2. Gel derived from a patient's own blood may help promote wound healing
   05-21-2007 · EurekAlert!
   A preliminary study suggests that topical application of a gel made from platelets in healthy individuals' own blood may help wounds heal more quickly and completely, according to a report in the May/June issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.
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3. Skin care: new research into scar-free healing
   01-21-2008 · EurekAlert!
   New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery.
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4. Botulism study could lead to new vaccines and treatments to counter bioterrorist attacks
   12-13-2006 · EurekAlert!
   Of all the weapons in the bioterrorist arsenal, none is as potent as botulinum neurotoxin, which causes botulism -- a potentially fatal disease with symptoms that include severe paralysis of the limbs and respiratory muscles. Of all the weapons in the bioterrorist arsenal, none is as potent as botulinum neurotoxin, which causes botulism -- a potentially fatal disease with symptoms that include severe paralysis of the limbs and respiratory muscles. Now, for the first time, scientists have figured out how this powerful neurotoxin disables individual nerve cells.
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5. Patient's own platelets may speed up skin wound healing
   05-21-2007 · EurekAlert!
   Treating skin wounds with a concentrated topical gel of the patient's own blood platelets may result in faster healing, says a researcher at the University of Cincinnati.
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6. Clean or boiled tap water is as good as saline at cleaning acute wounds
   01-22-2008 · EurekAlert!
   Using drinkable tap water to clean wounds does not increase infection rates, according to the findings of a Cochrane Review. There is, however, no evidence that it reduces infection rates or increases healing rate over leaving the wound alone.
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7. Study reveals molecular basis of botulism toxin's deadly activity
   12-14-2006 · EurekAlert!
   Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.
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8. Tiny tweezers and yeast help St. Jude show how cancer drug works
   07-09-2007 · EurekAlert!
   The annoying bulges of an over-wound telephone cord that shorten its reach and limit a caller's motion help to explain why drugs called camptothecins are so effective in killing cancer cells, according to investigators at St. Jude Children's Research Hospital and Delft University of Technology.
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9. JCI online early table of contents: Feb. 1, 2008
   02-01-2008 · EurekAlert!
   This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, Feb. 1, 2008, in the JCI, including: Timing is everything when using IL-7 to boost antiviral immunity; Precursor cells may provide clues to cardiac development; Ouch, Smad hurts! Smad7 may inhibit wound healing; Managing chronic pain; Genetic differences translated into functional diversity: New way to assess the importance of cross-reactive CD8+ T cells; and others.
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10. Botulism bug has few genome wrinkles
    05-23-2007 · EurekAlert!
    The genome of the organism that produces the world's most lethal toxin is revealed today. This toxin is the major weapon in the genome of Clostridium botulinum: less than two kg is enough to kill every person on the planet. The results, reported in Genome Research, show that C. botulinum doesn't have subtle tools to evade our human defences or tricky methods of acquiring resistance to antibiotics, but hits its host with a microbial sledgehammer.
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