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Dramatic results from combo therapy surprises Krabbé-disease researchers
01-09-2007 · EurekAlert!By all expectations, it shouldn't have worked as well as it did. A combination of bone marrow transplantation and gene therapy greatly lengthened the lives of laboratory mice doomed by a rapidly progressing, fatal neurodegenerative disorder also found in people.
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Keywords: dramatic, results, combo, therapy, surprises, krabbé-disease, researchers, result, surprise, krabbé, disease, researcher
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- Preventing tuberculosis reactivation
10-17-2007 · EurekAlert!
The researchers' results suggest that anti-TNF therapy is highly likely to lead to many incidents of TB if used in areas where exposure to the TB pathogen is probable. However, they also propose that a TNF-modulating agent could be developed that could balance the requirement for reduction of inflammation with the necessity to maintain resistance to infection and microbial disease.
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- Columbia research explores impact of gum disease therapy on pregnancy
11-01-2006 · EurekAlert!
A study published in the New England Journal of Medicine shows that treatment for periodontal disease in pregnant women does not result in a lower rate of adverse pregnancy outcomes such as preterm birth and low birth weight. At the same time, the study showed that periodontal treatment during pregnancy is safe. The researchers recommend additional studies to assess the potential benefits of the treatment.
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- Herceptin plus chemotherapy significantly increases disease-free survival in breast cancer
12-14-2006 · EurekAlert!
Combining the molecularly targeted therapy Herceptin with chemotherapy in women with early stage breast cancer significantly improves disease-free survival for patients with a specific genetic mutation that results in very aggressive disease, a top UCLA researcher reported Thursday.
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- Jefferson neuroscientists show anti-inflammation molecule helps fight MS-like disease
11-11-2007 · EurekAlert!
An immune system messenger molecule that normally helps quiet inflammation could be an effective tool against multiple sclerosis. Neurology researchers at Jefferson Medical College have found that the protein interkeukin-27 (IL-27) helped block the onset or reverse symptoms in animals with an MS-like disease. The results suggest that IL-27 may someday be part of a therapy to temper over-active immune responses, which are thought to be at the heart of MS.
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- Study of drug therapy for compulsive buying yields a puzzle, Stanford researcher says
03-13-2007 · EurekAlert!
Researchers at the Stanford University School of Medicine say they are puzzled by findings from their new study indicating that an antidepressant, which previously showed promise in treating a behavioral disorder known as compulsive buying, did not result in a sustained benefit for the patients who took it.
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- One shot of gene therapy spreads through brain in animal study
10-08-2007 · EurekAlert!
By targeting a site in a mouse brain well connected to other areas, researchers successfully delivered a beneficial gene to the entire brain—after one injection of gene therapy. If these results in animals can be realized in people, researchers may have a potential method for gene therapy to treat a host of rare but devastating congenital human neurological disorders, such as Tay-Sachs disease.
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- New drug helps hepatitis C patients start antiviral therapy
10-30-2006 · EurekAlert!
A new drug that stimulates the production of blood platelets can enable patients infected with hepatitis C virus to take other antiviral medications they previously could not take to fight the disease, according to the results of a clinical trial led by a Duke University Medical Center researcher.
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- Cigarette smoke, alcohol damage hearts worse as combo
11-21-2007 · EurekAlert!
A new study shows that taking in smoky air and drinking alcohol basically nullify any potential heart benefit from drinking alcohol by itself. Researchers at the University of Alabama at Birmingham found that mice exposed to smoky air and fed a liquid diet containing ethanol, the intoxicating ingredient in alcohol, had a 4.7-fold increase in artery lesions, a key sign of advancing heart disease. The study appears in Free Radical Biology & Medicine.
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- Causes of global death and disease in the next 25 years
11-27-2006 · EurekAlert!
In 1993, the World Bank sponsored the 1990 Global Burden of Disease study carried out by researchers at Harvard University and the World Health Organization. Colin Mathers and Dejan Locar (from the World Health Organization, Geneva) have now updated the projections based on 2002 data on mortality and burden of disease and published their results in the international open-access journal PLoS Medicine.
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- Mayo Clinic Cancer Center -- Working on the tough cases
12-11-2006 · EurekAlert!
Mayo Clinic Cancer Center, in collaboration with researchers from the University of Iowa, today presented results of a Phase II clinical study indicating that an oral drug, tipifarnib, can stall or reverse disease progression for patients with relapsed aggressive non-Hodgkin lymphoma.
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