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A new target for the treatment of breast cancer
01-11-2007 · EurekAlert!The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. Berkeley Lab researchers have demonstrated that inhibiting the activity of the protease enzyme known as TACE can deprive tumor cells of a key factor needed for their proliferation. TACE is strongly present in a form of breast cancer which responds poorly to current therapies.
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Keywords: target, treatment, breast, cancer
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- JCI table of contents: Dec. 13, 2007
12-13-2007 · EurekAlert!
This release contains summaries, links to PDFs, and contact information for the following newsworthy papers to be published online, Dec. 13, 2007, in the JCI: Treatment with SN reduces injury to the brain following stroke; OutRAGEd by atherosclerosis; A Neu protein target in the treatment of breast cancers; The long and winding TRAIL to cancer; Stressed-out hearts put MEF2D to work; How an antibody makes the CD4+ T cell immune response more aggressive; and others.
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- HER-2 status predicts success of chemotherapy in breast cancer treatment, study finds
10-10-2007 · EurekAlert!
Researchers have found they can potentially target chemotherapy for breast cancer to only those women most likely to benefit, sparing the majority of patients from unnecessary side effects.
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- Disparities in breast cancer treatment shown for women with disabilities
11-06-2006 · EurekAlert!
Among women receiving treatment for early-stage breast cancer, patients with disabilities had higher breast cancer mortality rates and were less likely than other women to receive standard treatment following breast-conserving surgery, according to a study in the November 7 issue of the Annals of Internal Medicine.
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11-17-2006 · EurekAlert!
Doctor instrumental in research says this is dramatic leap forward in breast cancer treatment.
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- Molecular signature may identify cisplatin-sensitive breast tumors
04-19-2007 · EurekAlert!
Researchers at the Massachusetts General Hospital Cancer Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors. They also have discovered the molecular basis of this sensitivity, which may help identify patients most likely to benefit from cisplatin treatment.
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- Chemotherapy more effective when given before breast cancer surgery
05-10-2007 · EurekAlert!
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- Increasing radiation dose shortens treatment time for women who choose breast sparing treatment
05-29-2007 · EurekAlert!
Radiation therapy after lumpectomy for early-stage breast cancer can be safely delivered in higher daily doses to greatly reduce treatment time. This conclusion of a new Fox Chase Cancer Center study is good news for women who might opt to have a mastectomy instead of a lumpectomy because of the time commitment needed for the usual six-week radiation course with the breast-sparing surgical option.
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- The '2-week wait rule' is failing breast cancer patients
07-12-2007 · EurekAlert!
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- Linchpin gene may be useful target for new breast cancer therapies
09-15-2007 · EurekAlert!
University of Iowa researchers have discovered a gene that plays a linchpin role in the ability of breast cancer cells to respond to estrogen. The finding may lead to improved therapies for hormone-responsive breast cancers, and may explain differences in the effectiveness of current treatments.
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- Ireland Cancer Center researcher finds standard treatment for breast cancer not followed
12-21-2007 · EurekAlert!
Research out of the Ireland Cancer Center of University Hospitals Case Medical Center, in collaboration with six integrated health plans that are part of the Cancer Research Network, found that the majority of older women with early stage breast cancer fail to adhere to the standard of treatment -- five years of daily oral use of the chemo-prevention drug Tamoxifen.
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