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Regulatory T cells require WASp if they are to prevent self-destruction
01-11-2007 · EurekAlert!In humans, mutation of the gene encoding a protein known as WASp leads to susceptibility to infections and systemic autoimmunity. Most studies have focused on understanding how WASp deficiency causes defects in T cell activation, but a new study shows that in mice and humans a population of T cells known as regulatory T cells, which prevent other immune cells attacking the body's and causing autoimmunity, are also impaired in the absence of WASp.
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Keywords: regulatory, cells, require, wasp, prevent, self-destruction, cell, self, destruction
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