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Early life family structure and microbially induced cancer risk and more

In a 28-year study of 261 Japanese-American men who carried Helicobacter pylori belonging to a large family or being born later in the family was associated with a significantly increased risk of developing gastric adenocarcinoma late in life.

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Keywords: life, family, structure, microbially, induced, cancer, risk

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1. Family structure size could affect breast cancer risk prediction accuracy for BRCA gene testing
   06-19-2007 · EurekAlert!
   Researchers have found that the probability of the breast cancer gene mutation BRCA among women with a history of breast cancer is greater when the number of older, female relatives in the family is smaller, according to a study in the June 20 issue of JAMA. This finding may challenge the accuracy of some breast cancer prediction models, which may not take family structure into account.
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2. Birth records hold pancreatic cancer clue
   08-15-2007 · EurekAlert!
   Pregnancies in Jerusalem in the 1960s and 1970s may hold vital clues about how pancreatic cancer and diabetes are linked. According to research published in the online open access journal BMC Medicine, women with a history of gestational diabetes had a higher risk of developing pancreatic cancer later in life.
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3. Gene markers located for hereditary prostate cancer
   01-16-2008 · EurekAlert!
   Researchers at the Johns Hopkins Brady Urological Institute, Wake Forest University and the Karolinska Institute in Sweden have identified an array of gene markers for hereditary prostate cancer that, along with family history for the disease, appear to raise risk to more than nine times that of men without such markers. The panel, gleaned from a study of more than 4,000 Swedes, found that these markers are common and could account for nearly half of the prostate cancer cases in this study.
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4. Racial and ethnic differences in colorectal cancer emphasize importance of screening
   10-15-2007 · EurekAlert!
   Minorities are at increased risk for colorectal cancer than Caucasians, but less likely to undergo life-saving screening tests. More African-Americans had proximal advanced polyps than Caucasians, and when compared to Latin Americans, both shared similar colonoscopy findings.
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5. Stress may increase a woman's risk of developing cervical cancer
   02-15-2008 · EurekAlert!
   A woman's daily stress can reduce her ability to fight off a common sexually transmitted disease and increase her risk of developing the cancer it can cause, according to a new study. No such association is seen, however, between past major life events, such as divorce or job loss, and the body's response to the infection.
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6. Brain pattern associated with genetic risk of obsessive compulsive disorder
   11-25-2007 · EurekAlert!
   Cambridge researchers have discovered that individuals with obsessive compulsive disorder and their close family members have distinctive patterns in their brain structure. This is the first time that scientists have associated an anatomical trait with familial risk for the disorder.
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7. Other highlights in the Dec. 6 JNCI
   12-05-2006 · EurekAlert!
   Other highlights in the Dec. 6 JNCI include an Italian model that predicts the risk of breast cancer, a study showing chemotherapy can cause a cognitive decline in some patients, a common genetic variant that is linked to drug-induced diarrhea, a protein that signals poor prognosis in some breast cancer patients and specific genetic changes that are linked to colon cancer in smokers.
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8. New protein super-family discovered with critical functions for animal life
   02-13-2007 · EurekAlert!
   Biologists have discovered a new super-family of developmental proteins that are critical for cell growth and differentiation and whose further study is expected to benefit research on cancer and the nerve-cell repair. The protein super-family, which existed before the emergence of animals about 850 million years ago, is of major importance for understanding how life evolved in primordial times. The discovery will be described in the February 14, 2007 issue of the journal PLoS ONE.
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9. Neither abortion nor miscarriage associated with breast cancer risk
   04-23-2007 · EurekAlert!
   Neither induced abortion nor spontaneous abortion (miscarriage) appears to be associated with breast cancer risk in premenopausal women, according to a report in the April 23 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
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10. Should children be permitted to get genetic testing for BRCA 1/2 mutations?
    01-15-2008 · EurekAlert!
    It's an ethical dilemma with serious implications. Should children be tested for gene mutations that predispose them to developing breast cancer and/or ovarian cancer later in life? New research suggests the next generation of parents may support testing minors even when any steps to reduce that risk will be postponed until adulthood -- a finding that challenges current policies.
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