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UA researchers find smallest cellular genome

10-12-2006 · EurekAlert!

The smallest collection of genes ever found for a cellular organism comes from tiny symbiotic bacteria that live inside special cells inside a small insect. Just 182 genes, the 160-kilobase genome could revise ideas about what's needed for a cell to work. The finding also provides new insight into bacterial evolution.

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  1. Researchers Find Smallest Cellular Genome
    10-14-2006 · ScienceDaily
    The smallest collection of genes ever found for a cellular organism comes from tiny symbiotic bacteria that live inside special cells inside a small insect. Just 182 genes, the 160-kilobase genome could revise ideas about what's needed for a cell to work. The finding also provides new insight into bacterial evolution.
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  2. Vet medicine researcher examines link between cancer, Down syndrome
    02-04-2008 · EurekAlert!
    There's new hope for breast cancer research, and it's coming from a very unlikely place. Researchers at the Texas A&M University College of Veterinary Medicine & Biomedical Sciences recently published articles in the journals Molecular and Cellular Biology and Carcinogenesis indicating that a protein long suspected to play a role in Down Syndrome may also contribute to treating this devastating disease.
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  3. The wider view from a detailed focus
    06-13-2007 · EurekAlert!
    A major study of the organization and regulation of the human genome published today changes our concept of how our genome works. The exhaustive analysis of 1 percent of the genome gives an extensive view of genetic activity alongside the cellular machinery that allows DNA to be read and replicated. The complex tapestry of interwoven elements revealed today suggests that "our perspective of transcription and genes may have to evolve," the researchers state.
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  4. Copy number variation may stem from replication misstep
    12-27-2007 · EurekAlert!
    Genome rearrangements, resulting in variations in the numbers of copies of genes, occur when the cellular process that copies DNA during cell division stalls and then switches to a different genetic "template," said researchers at Baylor College of Medicine in Houston in a report that appears today in the journal Cell.
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  5. Itsy bitsy genome
    10-28-2006 · Science News Online
    Researchers have sequenced the smallest genome yet discovered, a string of DNA belonging to a species of bacterium that lives inside sap-eating insects' guts.
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  6. As personal genomics stands poised to go mainstream, researchers urge caution
    09-20-2007 · EurekAlert!
    Imagine this: you visit your clinician, undergo genetic testing and then you are handed a miniature hard drive containing your personal genome sequence, which is subsequently uploaded onto publicly accessible databases. This may sound like science fiction, but it is scientific fact, and it is already happening. In an article published in the journal Science, University of Alberta researcher Tim Caulfield and co-authors highlight the need to proceed cautiously when it comes to personal genomics.
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  7. Mayo Clinic Cancer Center -- individualizing treatment for multiple myeloma patients
    12-10-2006 · EurekAlert!
    Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient's chance of responding to the agent.
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    03-29-2007 · EurekAlert!
    In studies in mouse models, researchers at the University of California, San Diego (UCSD) School of Medicine have found that a cellular receptor involved in triggering cell death is also a necessary component of tissue repair and regeneration immediately following liver injury. This discovery could have implications for early intervention or therapy in liver disease such as cirrhosis or hepatitis.
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    08-06-2007 · EurekAlert!
    Transcription -- the transfer of DNA's genetic information through the synthesis of complementary molecules of messenger RNA -- forms the basis of all cellular activities. Yet little is known about the dynamics of the process -- how efficient it is or how long it takes. Now, researchers at the Albert Einstein College of Medicine of Yeshiva University have measured the stages of transcription in real time. Their unexpected findings have fundamentally changed the way transcription is understood.
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  10. Scientists uncover how hormones achieve their effects
    10-22-2007 · EurekAlert!
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