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Researchers develop new strategy for the treatment of CML
01-17-2007 · EurekAlert!Virginia Commonwealth University Massey Cancer Center researchers have identified an approach to enhance the activity of a new anti-cancer agent that has already shown impressive efficacy in the treatment of chronic myelogenous leukemia.
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Keywords: researchers, develop, strategy, treatment, cml, researcher
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- Infectious disease researchers develop basis for experimental melanoma treatment
12-07-2006 · EurekAlert!
While investigating a fungus known to cause an infection in people with AIDS, two grantees of the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, unexpectedly discovered a potential strategy for treating metastatic melanoma, one of the deadliest forms of skin cancer. The treatment approach, which involves combining an antibody with radiation, has since been further developed and is expected to enter early-stage human clinical studies in 2007.
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- Researchers develop criteria to detect bone mass deficiencies in children with chronic diseases
06-06-2007 · EurekAlert!
Pediatricians now have a practical tool to help determine whether children with chronic diseases like Crohn's, juvenile arthritis and anorexia nervosa -- or those undergoing cancer treatment -- are at increased risk for bone mass deficiencies, fracture or osteoporosis as they get older, according to a new study whose lead author is a researcher at Cincinnati Children's Hospital Medical Center.
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- Study suggests potential underlying cause for dementia after cancer treatment
11-06-2006 · EurekAlert!
Researchers at Wake Forest University School of Medicine have identified changes in brain chemistry that may be associated with the dementia that many cancer patients develop after whole-brain radiation treatment.
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- Tamiflu survives sewage treatment
10-02-2007 · EurekAlert!
Swedish researchers have discovered that oseltamivir (Tamiflu), an antiviral drug used to prevent and mitigate influenza infections, is not removed or degraded during normal sewage treatment. Consequently, in countries where Tamiflu is used at a high frequency, there is a risk that its concentration in natural waters can reach levels where influenza viruses in nature will develop resistance to it. Their study was published in the high-ranked journal PLoS ONE.
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- When Gleevec is not enough
11-07-2006 · EurekAlert!
Researchers at the Jackson Laboratory, in collaboration with scientists at Bristol-Myers Squibb Oncology, discovered is that imatinib does not inactivate all BCR-ABL signaling pathways in the cascade. Proteins called SRC kinases are still activated by BCR-ABL in imatinib-treated mouse leukemic cells. Treatment with dasatinib, which inhibits the SRC proteins as well as BCR-ABL, was not only more effective for CML, but also led to complete B-ALL remission.
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- Researchers develop novel method for treatment of sickle cell disease
11-07-2006 · EurekAlert!
Virginia Commonwealth University researchers have developed a unique anti-sickling agent that may one day be effective in treating sickle cell disease, a painful and debilitating genetic blood disorder that affects approximately 80,000 Americans.
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- New research may show why some prostate cancer recurs after treatment
10-11-2007 · EurekAlert!
Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within cancer cells, which suggests that cancer cells may develop the capacity to produce their own androgens.
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- Study shows new strategy for developing antidepressants
12-08-2007 · EurekAlert!
Researchers may be able to develop an antidepressant which takes effect almost immediately by directly targeting novel molecules in the brain instead of taking a less direct route, which can lead to longer times for medication to take effect, according to a new study presented at the American College of Neuropsychopharmacology Annual Meeting.
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- Researchers develop better membranes for water treatment, drug delivery
11-29-2007 · EurekAlert!
Researchers at the University of Illinois have developed a new generation of biomimetic membranes for water treatment and drug delivery. The highly permeable and selective membranes are based on the incorporation of the functional water channel protein Aquaporin Z into a novel A-B-A triblock copolymer.
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- Jefferson researchers develop combined procedure for uterine preservation in treating fibroids
12-05-2006 · EurekAlert!
Although fibroids can cause pelvic pain, abnormal vaginal bleeding and infertility, women of childbearing age often choose to forego treatment because the options don't guarantee fertility.In the December issue of The Female Patient, physicians at Thomas Jefferson University Hospital in Philadelphia present a case history of a 35-year-old woman whose numerous fibroids formed a large mass in her pelvic area that, when initially diagnosed, was of a size comparable to a full-term pregnancy.
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