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Motor protein plays key role in connecting neurons

A motor protein called myosin X runs the main road of a developing neuron, delivering to its tip a receptor that enables it to communicate with other neurons, scientists say.

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1. U-M scientists find new causes for neurodegeneration
   10-24-2007 · EurekAlert!
   Diseases that cause neurons to break down, such as Alzheimer's, continue to be elusive to scientists and resistant to treatments. A new finding from University of Michigan researchers demonstrates an unpredicted link between a virtually unknown signaling molecule and neuron health. In a study released in PNAS this week, Lois Weisman connects the loss of this molecule to massive neurodegeneration in the brain, which plays a key role in the survival of nervous system cells.
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2. Gene-bender proteins may sway to DNA
   12-04-2006 · EurekAlert!
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3. UCLA, Italian chemists move closer to solving Lou Gehrig's disease mystery
   06-27-2007 · EurekAlert!
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4. Mouse with myotonic dystrophy type 1 finds RNA binding proteins at heart of problem
   09-05-2007 · EurekAlert!
   A new mouse model for myotonic dystrophy - the most common form of adult-onset muscular dystrophy - helped Baylor College of Medicine researchers show that levels of CUGBP1, a protein that binds and controls the activity of the genetic material RNA, increase early in affected cells of the animals with the disease. This means CUGBP1 plays a key role in the disorder.
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5. Blinded by sFRP-1: A WNT signaling protein plays a key role in glaucoma
   02-14-2008 · EurekAlert!
   Increased pressure in the eye is a major risk factor for glaucoma, one of the main causes of visual impairment and blindness in the world. It is thought that impaired outflow of fluid from the eye causes glaucoma-associated increased pressure in the eye, and the authors of a new study have now shown that increased expression of the protein sFRP-1, an inhibitor of cell signaling through WNT proteins, seems to be responsible for this.
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6. Hepatitis C helicase unwinds DNA in a spring-loaded, 3-step process
   07-26-2007 · EurekAlert!
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7. RNA-binding protein key to understanding myotonic dystrophy type 1
   10-11-2007 · EurekAlert!
   Increased levels of a protein called CUGBP1 play an important role in the adult-onset form of muscular dystrophy called myotonic dystrophy type 1, said Baylor College of Medicine researchers in a report that appears today in the journal Molecular Cell.
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8. Cystic fibrosis proteins photographed interacting
   12-07-2007 · EurekAlert!
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    09-20-2007 · EurekAlert!
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