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Researchers develop marker that identifies energy-producing centers in nerve cells
02-01-2007 · EurekAlert!A protein that causes coral to glow is helping researchers at the University of Maryland School of Medicine to light up brain cells that are critical for the proper functioning of the central nervous system. This fluorescent marker protein may shed light on brain cell defects believed to play a role in various neurological diseases.
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- Mass. General researchers identify master cardiac stem cell
11-22-2006 · EurekAlert!
Researchers from the Massachusetts General Hospital Cardiovascular Research Center have discovered what appears to be a master cardiac stem cell, capable of differentiating into the three major cell types of the mammalian heart. In a report to appear in the journal Cell, receiving early online release, they describe identifying these progenitor cells in mice, cloning them from embryonic stem cells, and showing that cloned cells can differentiate into cardiac muscle, smooth muscle or endothelial cells.
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- Scientists produce neurons from human skin
02-22-2007 · EurekAlert!
Scientists from Université Laval's Faculty of Medicine have succeeded in producing neurons in vitro using stem cells extracted from adult human skin. This is the first time such an advanced state of nerve cell differentiation has been achieved from human skin, according to lead researcher Professor François Berthod. This breakthrough could eventually lead to revolutionary advances in the treatment of neurodegenerative illnesses such as Parkinson's disease.
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- UM researchers find new marker to identify cancer stem cells
12-03-2007 · EurekAlert!
Researchers at the University of Michigan Comprehensive Cancer Center have found a marker that can be used to identify stem cells in breast tumors, suggesting a potential simple test that could help determine the best treatment for breast cancer.
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- Human stem cells delay start of Lou Gehrig's disease in rats
10-15-2006 · EurekAlert!
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. The grafted stem cells develop into nerve cells that make substantial connections with existing nerves and do not themselves succumb to Lou Gehrig's, also known as amyotrophic lateral sclerosis (ALS). The study is published in this week's issue of Transplantation.
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- Researchers identify how to switch off cancer cell genes
11-12-2007 · EurekAlert!
A new study led by researchers at the University of Southern California identifies how genes are silenced in cancer cells through distinct changes in the density of nucleosomes within the cells.
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- Columbia scientists determine 3-dimensional structure of cell's 'fuel gauge'
02-08-2007 · EurekAlert!
Researchers at Columbia University Medical Center have uncovered the complex structure of a protein that serves as a central energy gauge for cells, providing crucial details about the molecule necessary for developing useful new therapies for diabetes and possibly obesity. A paper published online today in the journal Science details this structure, helping to explain one of the cell's most basic and critical processes.
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- Loss of cell's 'antenna' linked to cancer's development
06-28-2007 · EurekAlert!
Most normal vertebrate cells have cilia, small hair-like structures that protrude like antennae into the surrounding environment to detect signals that control cell growth. In a new study published in the June 29 issue of Cell, Fox Chase Cancer Center researchers describe the strong link between ciliary signaling and cancer, and identify the rogue engineers responsible for dismantling the cell's antenna.
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- Bone marrow microenvironment can contribute to blood cell disorder
06-14-2007 · EurekAlert!
Disorders of blood cells may begin in the biological environment where the cells develop, not just with the cells themselves, according to a study from researchers at the Massachusetts General Hospital and the Peter MacCallum Cancer Center in Melbourne, Australia.
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- Human Stem Cells Delay Start Of Lou Gehrig's Disease In Rats
10-15-2006 · ScienceDaily
Researchers at Johns Hopkins have shown that transplanting human stem cells into spinal cords of rats bred to duplicate Lou Gehrig's disease delays the start of nerve cell damage typical of the disease and slightly prolongs life. The grafted stem cells develop into nerve cells that make substantial connections with existing nerves and do not themselves succumb to Lou Gehrig's, also known as amyotrophic lateral sclerosis (ALS). The study is published in this week's issue of Transplantation.
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- Molecular 'marker' on stem cells aids research, perhaps therapies
12-04-2006 · EurekAlert!
A sugar molecule present on embryonic stem cells also has been found on the surface of a type of adult stem cell, a discovery that may help researchers isolate and purify adult stem cells for use in therapies aimed at bone healing, tendon repair and cartilage regeneration, researchers at UT Southwestern Medical Center report.
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