Daily non-political popular news in brief.
New mechanism underlying pain found
10-15-2006 · EurekAlert!Researchers at Johnson & Johnson Pharmaceutical Research & Development (J&JPRD) today announced that they have discovered a new molecular mechanism that may underlie neuropathic pain. The clearer understanding of the root-cause of chronic neuropathic pain, and the preclinical validation of new targets for pharmaceutical therapies shown in this research, together present an opportunity for the development of new ways to treat the severe pain associated with such common conditions or diseases as sciatica, diabetic neuropathy and shingles.
Read more »
Keywords: mechanism, underlying, pain
« Previous | Next »
Similar news on "New mechanism underlying pain found":
- Scientist's Persistence Sheds Light On Marine Science Riddle
09-29-2006 · ScienceDaily
When he started compiling an online database of seashells 15 years ago, Dr. Gary Rosenberg did not envision that his meticulous record-keeping would eventually shed light on a 40-year-old evolutionary debate.
The debate involves the mechanism underlying the island rule: that small animals isolated on islands evolve to be larger than their mainland relatives, and large animals evolve to be smaller.
Similar news · Read more »
- Mechanism of hallucinogens' effects discovered
01-31-2007 · EurekAlert!
The brain mechanism underlying the mind-bending effects of hallucinogens such as LSD, mescaline, and psilocybin has been discovered by neuroscientists. They said their discoveries not only shed light on the longtime mystery of how hallucinogens work, but that the findings also offer a pathway to understanding the function of drugs used to treat neuropsychiatric disorders, which are now being used largely without an understanding of their fundamental mechanism.
Similar news · Read more »
- Discovery of a molecular mechanism underlying limb architecture
10-25-2006 · EurekAlert!
A genetic study performed by Dr. Marie Kmita, a researcher at the Institut de Recherches Cliniques de Montréal, in collaboration with colleagues from the University of Geneva in Switzerland, sheds light on the origins of the architecture of arms and legs.
Similar news · Read more »
- Study Identifies Possible Mechanism For Brain Damage In Huntington's Disease
10-06-2006 · ScienceDaily
Researchers from the MassGeneral Institute for Neurodegenerative Disease have identified a possible mechanism underlying how the gene mutation that causes Huntington's disease leads to the degeneration and death of brain cells.
Similar news · Read more »
- Molecular pathway appears crucial in development of pulmonary fibrosis
12-12-2007 · EurekAlert!
A study led by Massachusetts General Hospital researchers may have found a key mechanism underlying idiopathic pulmonary fibrosis, a usually fatal lung disease for which transplantation is the only successful treatment.
Similar news · Read more »
- Cocaine high caused by interference in neuronal receiving stations
12-06-2006 · EurekAlert!
Researchers have found evidence for a fundamental molecular mechanism underlying the hyperactive high of cocaine. In studies with rats, they have traced the effect to interactions between two types of receiving stations in neurons for nerve signals from their neighbors. The researchers' studies in rats found that when the animals received cocaine, a component of a receptor for the neurotransmitter dopamine tends to grab onto a component of a receptor for glutamate. The result, they found, was interference with normal activation of this glutamate receptor.
Similar news · Read more »
- Scripps Research study reveals new activation mechanism for pain sensing channel
01-22-2007 · EurekAlert!
A group of scientists at the Scripps Research Institute has identified a mechanism that enables certain compounds to activate a pain sensing protein. The findings could lead to the development of potential new therapies for managing acute and chronic pain.
Similar news · Read more »
- TU Delft tracks the influence of a cancer inhibitor on a single DNA molecule
06-24-2007 · EurekAlert!
Researchers in Delft University of Technology’s Kavli Institute of Nanoscience in The Netherlands have cast new light on the workings of the important cancer inhibitor topotecan. Little had been known about the underlying molecular mechanism, but the Delft scientists can now view the effects of the medicine live at the levelin of a single DNA molecule. The research is being published this week in the journal Nature.
Similar news · Read more »
- UCLA study finds brain response differences in the way women with IBS anticipate and react to pain
01-08-2008 · EurekAlert!
UCLA researchers found that women with irritable bowel syndrome cannot effectively turn-off a pain modulation mechanism in the brain, which causes them to be more sensitive to abdominal pain, compared to women without IBS. The findings may lead to a greater understanding of the condition and new treatment approaches.
Similar news · Read more »
- sLRP1-alpha provides relief from neuropathic pain
12-03-2007 · EurekAlert!
Injury to peripheral nerves causes neuropathic pain. Normal pain relief therapies do not effectively provide relief from neuropathic pain. Further understanding of the molecular mechanisms underlying neuropathic pain is therefore essential to facilitate the development of new drugs and new research in rodents has provided evidence that a fragment of the protein LRP1 (sLRP1-alpha) attenuates neuropathic pain.
Similar news · Read more »
