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Soft-cell approach cuts animal tests
02-06-2007 · EurekAlert!A new way to test the safety of the air we breathe is proving faster, cheaper and more humane than exposing laboratory animals to airborne chemical hazards, say UNSW scientists. Researchers at the university's Chemical Safety and Applied Toxicology Laboratories have developed an animal-free alternative that exposes living human cells to air pollutants inside a small chamber. The breakthrough could fast-track scientific understanding of the threat to human health posed by thousands of airborne chemical compounds.
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Keywords: soft-cell, approach, cuts, animal, tests, soft, cell, cut, test
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- DNA-damage test could aid drug development
05-14-2007 · EurekAlert!
Researchers from Massachusetts Institute of Technology and Whitehead Institute have developed a cell culture test for assessing a compound's genetic toxicity that may prove dramatically cheaper than existing animal tests. This assay would allow genetic toxicity to be examined far earlier in the drug development process, making it much more efficient.
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- 'Modular' leukemia drug shows promise in early testing
06-28-2007 · EurekAlert!
A new type of engineered drug candidate has shown promise in treating chronic lymphocytic leukemia in both test tube and early animal tests, a new study shows. The agent represents a new class of agents called small modular immunopharmaceuticals. Called CD37-SMIP, the agent targets a protein called CD37 on the surface of these leukemia cells.
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- Human antibodies that block human and animal SARS viruses identified
07-02-2007 · EurekAlert!
An international team of investigators has identified the first human antibodies that can neutralize different strains of virus responsible for outbreaks of severe acute respiratory syndrome (SARS). The researchers used a mouse model and in vitro assays (lab tests) to test the neutralizing activity of the antibodies.
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- Team treatment for depression cuts medical costs
02-07-2008 · EurekAlert!
A team approach to treating depression in older adults, already shown to improve health, can also cut total health-care costs, according to a new study led by the University of Washington. The study appears in the February issue of the American Journal of Managed Care.
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- Fat stem cells being studied as option for breast reconstruction
10-26-2006 · EurekAlert!
Breast cancer survivors might one day avoid the prospect of invasive breast reconstruction surgery, opting instead for an approach that would involve using stem cells from their own fat, suggest researchers who are studying the potential these cells may have for regenerating new breast tissue. In animal models, they hope to prove that an injection of fat stem cells that are seeded onto microscopic scaffold structures will enable production of durable, replacement soft tissue.
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- Cloned Mice Created From Fully Differentiated Cells, A Milestone In Cloning Research
10-02-2006 · ScienceDaily
New research dismisses the notion that adult stem cells are necessary for successful animal cloning, proving instead that cells that have completely evolved to a specific type not only can be used for cloning purposes, but they may be better and more efficient. As proof, researchers report they created two mouse pups from a type of blood cell that itself is incapable of dividing to produce a second generation of its own kind.
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- The CReSA is working on a new strategy to combat spongiforms
10-31-2006 · EurekAlert!
Researchers at the Animal Health Research Centre (CReSA) are developing immunotherapeutical strategies against diseases produced by prion, such as Bovine Spongiform Encephalitis. The most recent results, published in the Journal of Virology, show that important advances have been made in tests using DNA vaccines on animal models, enabling a significant delay in the arrival of symptoms. In the long term, this research could lead to the production of treatment for humans.
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- Penn researchers link cell's protein recycling systems
06-13-2007 · EurekAlert!
Researchers have discovered a molecular link between the cell's two major pathways for breaking down proteins and have succeeded in using this link to rescue neurodegenerative diseases in a simple animal model.
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- Penn Veterinary Medicine report new strategy to create genetically modified animals
09-20-2007 · EurekAlert!
Researchers at Penn Vet have demonstrated a new strategy for genetic modification of large animals by employing a virus that transfers genetic modifications to male reproductive cells, which passes naturally to offspring. Scientists at the Center for Animal Transgenesis and Germ Cell Research at Penn introduced adeno-associated virus to germline stem cells in goats and mice. AAV stably transduced male germ line stem cells and led to transgene transmission through the male germ line.
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- Photo favourite: ATV rendezvous simulation
11-13-2006 · European Space Agency (ESA)
A choice from our ESA photo galleries
Tests conducted at Val de Reuil, France, to simulate the rendezvous of the Automated Transfer Vehicle (ATV) with the International Space Station (ISS). Sensors mounted on an articulated industrial robotic arm (image) acted as the ATV, whilst a 120-tonne mobile platform represented the ISS. During simulations the platform was made to approach the robotic arm in a motion identical to the one expected when the real vehicles rendezvous in space next year.
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