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Gene elevating breast cancer risk also causes prostate cancer

An international multicenter research effort has identified a new genetic defect as a potential heritable breast cancer susceptibility candidate. The same PALB2 mutation also seems to in some measure cause prostate cancer.

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Keywords: gene, elevating, breast, cancer, risk, causes, prostate, cause

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1. International study points to new breast cancer-susceptibility gene
   02-08-2007 · EurekAlert!
   A gene whose existence was detected only a couple of years ago may increase women's risk of breast cancer when inherited in a mutated form, and may contribute to prostate cancer as well, researchers at Dana-Farber Cancer Institute and colleagues in Finland report in a new study.
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2. Enhanced DNA-repair mechanism can cause breast cancer
   10-15-2007 · EurekAlert!
   Although defects in the "breast cancer gene," BRCA1, have long been known to increase the risk for breast cancer, exactly how the defects lead to tumor growth has remained a mystery. Now scientists provide insight into how the normal BRCA1 gene suppresses the growth of tumors as well as the nature of the genetic instability that leads to cancer when BRCA1 is defective.
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3. Other highlights in the Nov. 13 JNCI
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4. Other highlights in the March 7 JNCI
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5. Other Highlights in the Nov. 27 JNCI
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6. New study reveals for first time how BRCA1 mutations cause breast cancer
   12-09-2007 · EurekAlert!
   An international team of researchers led by Columbia University Medical Center's Herbert Irving Comprehensive Cancer Center and Sweden's Lund University has, for the first time, revealed how mutations in the BRCA1 gene lead to breast cancer. Findings show that one way BRCA1 mutations cause cancer is by knocking out a powerful tumor suppressor gene known as PTEN.
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7. BRCA1 mutation linked to breast cancer stem cells
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8. Gene markers located for hereditary prostate cancer
   01-16-2008 · EurekAlert!
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10. Other highlights in the Dec. 11 JNCI
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